Table 1. Presenting Features of Children... | American Society of Hematology

Table 1.

Presenting Features of Children With JMML

Characteristic	Category	No.	%
Clinical
Sex	Male	146	71
	Female	60	29
Age	<1 yr	72	40
	1 to <2 yr	36	20
	2 to <3 yr	25	14
	≥3 yr	46	26
Hepatomegaly		165	79
Splenomegaly		206	97
Lymphadenopathy		89	52
Skin involvement		78	48
Associated conditions	NF1	14	7
	Other conditions	17	9
Laboratory
Leukocyte count (×10⁹/L)	<50	144	70
	50-99	39	22
	≥100	14	8
Monocyte count (×10⁹/L)	<5	67	35
	5-9.9	45	32
	≥10	46	33
Percentage of blasts in peripheral blood	0-2	92	56
	>2	73	44
Hb level (g/dL)	>8-12	100	66
	<8	53	34
HbF level (%)	0-9	71	38
	≥10	117	62
Platelets count (×10⁹/L)	≥100	40	23
	99-50	54	30
	<50,000	80	47
Bone marrow blasts (%)	0-9	67	64
	10-20	27	26
	>20	12	10
Alkaline phosphatase score	Low	47	41
Cytogenetic analysis	Normal	132	68
	Monosomy 7	31	16
	Other abnormalities	32	16

Characteristic	Category	No.	%
Clinical
Sex	Male	146	71
	Female	60	29
Age	<1 yr	72	40
	1 to <2 yr	36	20
	2 to <3 yr	25	14
	≥3 yr	46	26
Hepatomegaly		165	79
Splenomegaly		206	97
Lymphadenopathy		89	52
Skin involvement		78	48
Associated conditions	NF1	14	7
	Other conditions	17	9
Laboratory
Leukocyte count (×10⁹/L)	<50	144	70
	50-99	39	22
	≥100	14	8
Monocyte count (×10⁹/L)	<5	67	35
	5-9.9	45	32
	≥10	46	33
Percentage of blasts in peripheral blood	0-2	92	56
	>2	73	44
Hb level (g/dL)	>8-12	100	66
	<8	53	34
HbF level (%)	0-9	71	38
	≥10	117	62
Platelets count (×10⁹/L)	≥100	40	23
	99-50	54	30
	<50,000	80	47
Bone marrow blasts (%)	0-9	67	64
	10-20	27	26
	>20	12	10
Alkaline phosphatase score	Low	47	41
Cytogenetic analysis	Normal	132	68
	Monosomy 7	31	16
	Other abnormalities	32	16

Data from ^{11,13,15,20,29-43}. Certain features are not reported for all patients.