Cytotoxicity of T Cells or T-Cell Subsets Using 51Chromium Against MC-38 Targets
Experiment No. 1 . | Experiment No. 2 . | Experiment No. 3 . | Experiment No. 4 . | ||||
---|---|---|---|---|---|---|---|
E:T ratio . | % Specific Lysis . | E:T Ratio . | % Specific Lysis . | E:T Ratio . | % Specific Lysis . | E:T Ratio . | % Specific Lysis . |
25:1 | 6.6 | 42:1 | 11.2 | 42:1 | 16.1 | 42:1 | 13.2 |
12.5:1 | 5.8 | 21:1 | 10.9 | 21:1 | 11.6 | 21:1 | 12.9 |
6.25:1 | 5.3 | 10:1 | 11.4 | 10:1 | 13.1 | 10:1 | 12.5 |
3:1 | 5.8 | 5:1 | 13.6 | 5:1 | 7.9 | 5:1 | 11.9 |
Experiment No. 1 . | Experiment No. 2 . | Experiment No. 3 . | Experiment No. 4 . | ||||
---|---|---|---|---|---|---|---|
E:T ratio . | % Specific Lysis . | E:T Ratio . | % Specific Lysis . | E:T Ratio . | % Specific Lysis . | E:T Ratio . | % Specific Lysis . |
25:1 | 6.6 | 42:1 | 11.2 | 42:1 | 16.1 | 42:1 | 13.2 |
12.5:1 | 5.8 | 21:1 | 10.9 | 21:1 | 11.6 | 21:1 | 12.9 |
6.25:1 | 5.3 | 10:1 | 11.4 | 10:1 | 13.1 | 10:1 | 12.5 |
3:1 | 5.8 | 5:1 | 13.6 | 5:1 | 7.9 | 5:1 | 11.9 |
Effectors in experiment 1: CD4+ T cells from naive mice; effectors in experiment 2: splenocytes from cured mice; effectors in experiment 3: CD4+ T cells from cured mice; effectors in experiment 4: CD8+ T cells from cured mice.