Effects of HU on Expression of CD49d ( α4) and CD36 on Sickle Cell Erythrocytes
| . | . | Baseline . | HU . | P . |
|---|---|---|---|---|
| CD49d | % Retic+ | 29.0 ± 5.9 | 14.9 ± 2.3 | .0003 |
| (α4) | ||||
| # Retic+ | 129 ± 39 | 48 ± 18 | .0008 | |
| (× 103/μL) | ||||
| % RBC+ | 5.2 ± 1.8 | 2.3 ± 1.0 | .0078 | |
| # RBC+ | 139 ± 36 | 58 ± 15 | .0011 | |
| (× 103/μL) | ||||
| CD36 | % Retic+ | 55.3 ± 6.4 | 42.6 ± 8.9 | .0046 |
| (GPIV) | ||||
| # Retic+ | 245 ± 60 | 141 ± 67 | .0054 | |
| (× 103/μL) | ||||
| % RBC+ | 15.8 ± 3.8 | 14.2 ± 5.0 | .4349 | |
| # RBC+ | 441 ± 133 | 357 ± 74 | .1718 | |
| (× 103/μL) |
| . | . | Baseline . | HU . | P . |
|---|---|---|---|---|
| CD49d | % Retic+ | 29.0 ± 5.9 | 14.9 ± 2.3 | .0003 |
| (α4) | ||||
| # Retic+ | 129 ± 39 | 48 ± 18 | .0008 | |
| (× 103/μL) | ||||
| % RBC+ | 5.2 ± 1.8 | 2.3 ± 1.0 | .0078 | |
| # RBC+ | 139 ± 36 | 58 ± 15 | .0011 | |
| (× 103/μL) | ||||
| CD36 | % Retic+ | 55.3 ± 6.4 | 42.6 ± 8.9 | .0046 |
| (GPIV) | ||||
| # Retic+ | 245 ± 60 | 141 ± 67 | .0054 | |
| (× 103/μL) | ||||
| % RBC+ | 15.8 ± 3.8 | 14.2 ± 5.0 | .4349 | |
| # RBC+ | 441 ± 133 | 357 ± 74 | .1718 | |
| (× 103/μL) |
Baseline = value at the time of the first measurement of adhesion receptor expression. HU = value at the time of the last measurement of adhesion receptor expression while on HU.
Abbreviations: Retic, reticulocyte; GPIV, glycoprotein IV.