Summary of the Frequencies of Euploid Fetal Cells Detected in NEC and CD34+ Fractions From Maternal PB and the Positive and Negative Predictive Value of These Tests
| Sorted Subpopulation . | Frequency of Fetal Cells per 20 mL . | Positive Predictive Value (%) . | Negative Predictive Value (%) . |
|---|---|---|---|
| . | (2 × 107 cells) . | . | . |
| Frozen maternal PB (n = 27) | |||
| PB NEC fractions | 0-14 | 75 | 17 |
| PB CD34+ fraction | 0-7 | 89 | 27 |
| PB CD34+ fraction cultured for 5 d | 0-35 | 89 | 33 |
| Combined results | 0-35 | 84 | 26 |
| Nonfrozen maternal PB (n = 10) | |||
| PB NEC fractions | 0-68 | 75 | 33 |
| PB CD34+ fraction | 0-42 | 67 | 25 |
| PB CD34+ fraction cultured for 5 d | 0-93 | 67 | 25 |
| Combined results | 0-93 | 70 | 28 |
| Sorted Subpopulation . | Frequency of Fetal Cells per 20 mL . | Positive Predictive Value (%) . | Negative Predictive Value (%) . |
|---|---|---|---|
| . | (2 × 107 cells) . | . | . |
| Frozen maternal PB (n = 27) | |||
| PB NEC fractions | 0-14 | 75 | 17 |
| PB CD34+ fraction | 0-7 | 89 | 27 |
| PB CD34+ fraction cultured for 5 d | 0-35 | 89 | 33 |
| Combined results | 0-35 | 84 | 26 |
| Nonfrozen maternal PB (n = 10) | |||
| PB NEC fractions | 0-68 | 75 | 33 |
| PB CD34+ fraction | 0-42 | 67 | 25 |
| PB CD34+ fraction cultured for 5 d | 0-93 | 67 | 25 |
| Combined results | 0-93 | 70 | 28 |
Positive predictive value refers to the probability that the fetus is male given that the FACS/FISH method predicts that the fetus is male. Negative predictive value refers to the probability that the fetus is female given that the FACS/FISH method predicts that the fetus is not male.