Demographic, Clinical, and Laboratory Characteristics of Patients Undergoing Elective Open-Heart Surgery Given 5 × 500 U/kg BW Epoetin Beta Placebo Intravenously Within 14 Days Preoperatively
| . | Mean ± SD in Trial Group . | Difference Between Means (95% CI) . | |
|---|---|---|---|
| . | Epoetin Beta (n = 36) . | Placebo (n = 36) . | . |
| Male/female (n) | 28/8 | 28/8 | — |
| Age (yr) | 54.3 ± 8.6 | 57.0 ± 8.8 | −2.7 (−6.8-1.4) |
| BW (kg) | 79.1 ± 14.1 | 75.4 ± 11.7 | 3.7 (−2.4-9.8) |
| Height (cm) | 171.9 ± 8.8 | 170.3 ± 7.3 | 1.6 (−2.2-5.5) |
| Blood volume (mL)* | 4945.7 ± 822.5 | 4762.5 ± 699.4 | 183 (−178-544) |
| LVEF (%) | 53.9 ± 17.2 | 50.9 ± 14.5 | 3.0 (−4.8-10.9) |
| Ischemia time (min) | 46.6 ± 17.9 | 46.6 ± 16.0 | 0.0 (−8.0-8.1) |
| CPB time (min) | 78.4 ± 22.3 | 79.4 ± 18.6 | −1.0 (11.1-9.1) |
| Total blood loss (mL) | 855 (595-1030)† | 695 (565-1050)† | 70 (−70-230)‡ |
| Physical status (%)ρ | |||
| ASA II | 5.5 | 11.1 | — |
| ASA III | 94.5 | 88.9 | — |
| . | Mean ± SD in Trial Group . | Difference Between Means (95% CI) . | |
|---|---|---|---|
| . | Epoetin Beta (n = 36) . | Placebo (n = 36) . | . |
| Male/female (n) | 28/8 | 28/8 | — |
| Age (yr) | 54.3 ± 8.6 | 57.0 ± 8.8 | −2.7 (−6.8-1.4) |
| BW (kg) | 79.1 ± 14.1 | 75.4 ± 11.7 | 3.7 (−2.4-9.8) |
| Height (cm) | 171.9 ± 8.8 | 170.3 ± 7.3 | 1.6 (−2.2-5.5) |
| Blood volume (mL)* | 4945.7 ± 822.5 | 4762.5 ± 699.4 | 183 (−178-544) |
| LVEF (%) | 53.9 ± 17.2 | 50.9 ± 14.5 | 3.0 (−4.8-10.9) |
| Ischemia time (min) | 46.6 ± 17.9 | 46.6 ± 16.0 | 0.0 (−8.0-8.1) |
| CPB time (min) | 78.4 ± 22.3 | 79.4 ± 18.6 | −1.0 (11.1-9.1) |
| Total blood loss (mL) | 855 (595-1030)† | 695 (565-1050)† | 70 (−70-230)‡ |
| Physical status (%)ρ | |||
| ASA II | 5.5 | 11.1 | — |
| ASA III | 94.5 | 88.9 | — |