Staining of Biopsy Material of Patients Treated With RFT5-SMPT-dgA and Clinical Response
| Patient No. . | Biopsy . | H-RS Cells . | % CD25+ H-RS Cells . | % CD30+ H-RS Cells . | Response . |
|---|---|---|---|---|---|
| 1 | ND | ND | ND | ND | PD |
| 2 | Lymph node | +++ | ≥30% | ≥90% | MR |
| 3 | Lymph node | NE | NE | NE | SD |
| 4 | ND | ND | ND | ND | PD |
| 5 | ND | ND | ND | ND | SD |
| 6 | Lymph node | +++ | ≥30% | ≥90% | PD |
| 7 | ND | ND | ND | ND | SD |
| 8 | ND | ND | ND | ND | PD |
| 9 | Lung | +++ | ≥30% | ≥90% | PD |
| 10 | Lymph node | ++ | ≥40% | ≤10% | PR |
| 11 | Lymph node | ++ | ≥35% | ≥50% | PD |
| 12 | Liver | + | ≥30% | ≥50% | PR |
| 13 | ND | ND | ND | ND | PD |
| 14 | ND | ND | ND | ND | PD |
| 15 | ND | ND | ND | ND | PD |
| Patient No. . | Biopsy . | H-RS Cells . | % CD25+ H-RS Cells . | % CD30+ H-RS Cells . | Response . |
|---|---|---|---|---|---|
| 1 | ND | ND | ND | ND | PD |
| 2 | Lymph node | +++ | ≥30% | ≥90% | MR |
| 3 | Lymph node | NE | NE | NE | SD |
| 4 | ND | ND | ND | ND | PD |
| 5 | ND | ND | ND | ND | SD |
| 6 | Lymph node | +++ | ≥30% | ≥90% | PD |
| 7 | ND | ND | ND | ND | SD |
| 8 | ND | ND | ND | ND | PD |
| 9 | Lung | +++ | ≥30% | ≥90% | PD |
| 10 | Lymph node | ++ | ≥40% | ≤10% | PR |
| 11 | Lymph node | ++ | ≥35% | ≥50% | PD |
| 12 | Liver | + | ≥30% | ≥50% | PR |
| 13 | ND | ND | ND | ND | PD |
| 14 | ND | ND | ND | ND | PD |
| 15 | ND | ND | ND | ND | PD |
Abbreviations: ND, not done; NE, not evaluable; +, few; ++, moderate; +++, many.