Relationship Between p53 Status, bcl-2 Expression, and MIB-1, and Response to EPOCH
| Variable . | No. of Patients (%) . | P2 . | ||
|---|---|---|---|---|
| . | CR . | PR . | NR . | . |
| p53 status | ||||
| + | 2 (13) | 5 (31) | 9 (56) | |
| − | 15 (25) | 34 (58) | 10 (17) | .01 |
| bcl-2 expression | ||||
| 0/1 | 8 (28) | 15 (52) | 6 (21) | |
| 2/3 | 6 (15) | 23 (58) | 11 (28) | .42 |
| MIB-1 | ||||
| <80% | 8 (16) | 27 (53) | 16 (31) | |
| ≥80% | 7 (44) | 8 (50) | 1 (6) | .028 |
| Variable . | No. of Patients (%) . | P2 . | ||
|---|---|---|---|---|
| . | CR . | PR . | NR . | . |
| p53 status | ||||
| + | 2 (13) | 5 (31) | 9 (56) | |
| − | 15 (25) | 34 (58) | 10 (17) | .01 |
| bcl-2 expression | ||||
| 0/1 | 8 (28) | 15 (52) | 6 (21) | |
| 2/3 | 6 (15) | 23 (58) | 11 (28) | .42 |
| MIB-1 | ||||
| <80% | 8 (16) | 27 (53) | 16 (31) | |
| ≥80% | 7 (44) | 8 (50) | 1 (6) | .028 |
Statistically significant P values are shown in boldface.
Abbreviations: CR, complete response; PR, partial response; NR, no response.