p53 Mutations
| Patient No. . | Histology . | p53 IHC . | p53 Mutations . | |
|---|---|---|---|---|
| . | . | . | Exon . | Codon-Mutation . |
| 1 | DLC | + | 5 | 35-bp insertion |
| 2 | DLC | + | 5 | 176 TGC(Cys)→TCC(Ser) |
| 3 | DLC | + | 7 | 241 TCC(Ser)→CCC(Pro) |
| 4 | FSC & DLC | + | 7 | 248 CGG(Arg)→CAG(Gln) |
| 5 | DLC | + | 7 | 236 TAC(Tyr)→AAC(Asn) |
| 6 | DLC | + | 7 | 244 GGC(Gly)→ACC(Thr) |
| 7 | DLC | + | 7 | 236 TAC(Tyr)→AAC(Asn) |
| 8 | F & DLC | + | 8 | 273 CGT(Arg)→CAT(His) |
| 9 | FM | + | 8 | 278 CCT(Pro)→TCT(Ser) |
| 10 | FM | + | 8 | 281 GAC(Asp)→GTC(Val) |
| 11 | DLC | + | 8 | 281 GAC(Asp)→AAC(Asn) |
| 12 | DLC | + | — | — |
| 13 | DLC | + | NA | NA |
| 14 | DLC | − | 6 | 192 CAG(Gln)→TAG(Stop) |
| 15 | DLC | − | 6 | 215 AGT(Ser)→AAT(Asn) |
| 16 | DLC | − | 7 | 248 CGG(Arg)→CAG(Gln) |
| Patient No. . | Histology . | p53 IHC . | p53 Mutations . | |
|---|---|---|---|---|
| . | . | . | Exon . | Codon-Mutation . |
| 1 | DLC | + | 5 | 35-bp insertion |
| 2 | DLC | + | 5 | 176 TGC(Cys)→TCC(Ser) |
| 3 | DLC | + | 7 | 241 TCC(Ser)→CCC(Pro) |
| 4 | FSC & DLC | + | 7 | 248 CGG(Arg)→CAG(Gln) |
| 5 | DLC | + | 7 | 236 TAC(Tyr)→AAC(Asn) |
| 6 | DLC | + | 7 | 244 GGC(Gly)→ACC(Thr) |
| 7 | DLC | + | 7 | 236 TAC(Tyr)→AAC(Asn) |
| 8 | F & DLC | + | 8 | 273 CGT(Arg)→CAT(His) |
| 9 | FM | + | 8 | 278 CCT(Pro)→TCT(Ser) |
| 10 | FM | + | 8 | 281 GAC(Asp)→GTC(Val) |
| 11 | DLC | + | 8 | 281 GAC(Asp)→AAC(Asn) |
| 12 | DLC | + | — | — |
| 13 | DLC | + | NA | NA |
| 14 | DLC | − | 6 | 192 CAG(Gln)→TAG(Stop) |
| 15 | DLC | − | 6 | 215 AGT(Ser)→AAT(Asn) |
| 16 | DLC | − | 7 | 248 CGG(Arg)→CAG(Gln) |
Abbreviations: IHC, immunohistochemistry; NA, tissue not available; DLC, diffuse large-cell/immunoblastic lymphoma; FSC, follicular small cleaved; F, follicular; FM, follicular mixed.