Correlation of gene expression for the thioredoxin-related proteins with the worst prognosis, as measured by the patient outcome predictor scores
. | Average expression on microarray† . | . | Statistical significance . | . | . | |||
|---|---|---|---|---|---|---|---|---|
| Gene . | Best prognosis, 10% . | Worst prognosis, 10% . | t test, best 10% vs worst 10%, P . | Regression, all patients, P . | Correlation with poor prognosis . | |||
| Thioredoxin (TRX) | –0.055 | 0.0994 | .397 | .15 | Increasing trend | |||
| Vitamin D3 up-regulated protein 1 (VDUP1/TIP/TBP2) | 0.1916 | –0.6775 | < .001* | .005* | Significant decrease | |||
| Thioredoxin reductase 1 (TRXR1) | 0.1648 | 0.0036 | .177 | .098 | Decreasing trend | |||
| Thioredoxin reductase 2 (TRXR2) | 0.0719 | –0.1768 | .033* | .491 | Significant decrease/no change | |||
. | Average expression on microarray† . | . | Statistical significance . | . | . | |||
|---|---|---|---|---|---|---|---|---|
| Gene . | Best prognosis, 10% . | Worst prognosis, 10% . | t test, best 10% vs worst 10%, P . | Regression, all patients, P . | Correlation with poor prognosis . | |||
| Thioredoxin (TRX) | –0.055 | 0.0994 | .397 | .15 | Increasing trend | |||
| Vitamin D3 up-regulated protein 1 (VDUP1/TIP/TBP2) | 0.1916 | –0.6775 | < .001* | .005* | Significant decrease | |||
| Thioredoxin reductase 1 (TRXR1) | 0.1648 | 0.0036 | .177 | .098 | Decreasing trend | |||
| Thioredoxin reductase 2 (TRXR2) | 0.0719 | –0.1768 | .033* | .491 | Significant decrease/no change | |||