Table 1. Correlation of antioxidant... | American Society of Hematology

Table 1.

Correlation of antioxidant enzyme gene expression with prognosis as measured by the patient outcome predictor scores

	Average expression on microarray†			Statistical significance
Gene	Best prognosis, 10%	Worst prognosis, 10%	t test, best 10% versus worst 10%, P	Regression, all patients, P
Decreasing expression with poor prognosis
Mn superoxide dismutase (SOD2)	0.2632	-0.5577	.011^*	.000^*
Extracellular superoxide dismutase (SOD3)	0.1759	-0.6345	.008^*	.031^*
Glutathione peroxidase (GPX1,3,4)	0.1254	-0.1428	.080	.012^*
Catalase	0.1079	-0.3076	.042^*	.191
No change with prognosis
Cu,Zn superoxide dismutase (SOD1)	0.1885	0.1845	.985	.331
Increasing expression with poor prognosis
Peroxiredoxin 3 (PRX3)	-0.0722	0.1009	.173	.040^*
Peroxiredoxin 4 (PRX4)	-0.0365	0.3623	.068	.008^*

	Average expression on microarray†			Statistical significance
Gene	Best prognosis, 10%	Worst prognosis, 10%	t test, best 10% versus worst 10%, P	Regression, all patients, P
Decreasing expression with poor prognosis
Mn superoxide dismutase (SOD2)	0.2632	-0.5577	.011^*	.000^*
Extracellular superoxide dismutase (SOD3)	0.1759	-0.6345	.008^*	.031^*
Glutathione peroxidase (GPX1,3,4)	0.1254	-0.1428	.080	.012^*
Catalase	0.1079	-0.3076	.042^*	.191
No change with prognosis
Cu,Zn superoxide dismutase (SOD1)	0.1885	0.1845	.985	.331
Increasing expression with poor prognosis
Peroxiredoxin 3 (PRX3)	-0.0722	0.1009	.173	.040^*
Peroxiredoxin 4 (PRX4)	-0.0365	0.3623	.068	.008^*

Significant P value

Values are on a log2 scale