Table 2.

Lymphoma phenotypes induced upon SL3-3 MLV infection


Phenotype

Total

WT

Nfatc2-/-

Nfatc3-/-
One dominant phenotypic cell population  38*  NA   NA   NA  
   Immature CD4-CD8- DN   5   2   3   0  
   Immature CD4+CD8+ DP   17   8   3   6  
   Mature CD4-CD8+ SP   8   3   2   2  
   Mature CD4+CD8- SP   8   6   1   2  
Two dominant phenotypic cell populations  11  NA   NA   NA  
   CD4+CD8+DP / CD4-CD8+ SP   9   3   4   2  
   CD4+CD8+DP / CD4+CD8-
 
2
 
0
 
1
 
1
 

Phenotype

Total

WT

Nfatc2-/-

Nfatc3-/-
One dominant phenotypic cell population  38*  NA   NA   NA  
   Immature CD4-CD8- DN   5   2   3   0  
   Immature CD4+CD8+ DP   17   8   3   6  
   Mature CD4-CD8+ SP   8   3   2   2  
   Mature CD4+CD8- SP   8   6   1   2  
Two dominant phenotypic cell populations  11  NA   NA   NA  
   CD4+CD8+DP / CD4-CD8+ SP   9   3   4   2  
   CD4+CD8+DP / CD4+CD8-
 
2
 
0
 
1
 
1
 

NA indicates not applicable.

*

Nine of these 38 tumors were analyzed by immunohistochemistry

Two of these 11 tumors were analyzed by immunohistochemistry

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