Table 2.

Increased amount of orthochromatic normoblasts in Mekk1ΔKD and Jnk2-/- MEKK1ΔKD fetuses



Genotype
Wt*
Mekk1ΔKD
Jnk2-/- Mekk1ΔKD
Stage
Orthochromatic normoblasts in circulation, %
N
Orthochromatic normoblasts in circulation, %
N
Orthochromatic normoblasts in circulation, %
N
E11.5   100 ± 0   5   ND   ND   ND   ND  
E12.5   83 ± 4   6   ND   ND   ND   ND  
E13.5   44 ± 14   8   64   1   ND   ND  
E14.5   23 ± 8   7   72 ± 15  6   83 ± 10  7  
E15.5   2 ± 3   6   80   1   50 ± 15  6  
E16.5
 
0 ± 0
 
7
 
74
 
1
 
ND
 
ND
 


Genotype
Wt*
Mekk1ΔKD
Jnk2-/- Mekk1ΔKD
Stage
Orthochromatic normoblasts in circulation, %
N
Orthochromatic normoblasts in circulation, %
N
Orthochromatic normoblasts in circulation, %
N
E11.5   100 ± 0   5   ND   ND   ND   ND  
E12.5   83 ± 4   6   ND   ND   ND   ND  
E13.5   44 ± 14   8   64   1   ND   ND  
E14.5   23 ± 8   7   72 ± 15  6   83 ± 10  7  
E15.5   2 ± 3   6   80   1   50 ± 15  6  
E16.5
 
0 ± 0
 
7
 
74
 
1
 
ND
 
ND
 

Plus/minus values represent standard deviation. Values that are given without standard deviation are for cases in which only one mouse was analyzed.

ND indicates not determined.

*

Jnk2-/- and Mekk1ΔKD/+ were identical to wt.

P < .05 compared with wt.

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