IFN-γ production by T cells from patients with CLL stimulated with autologous CLL cells
. | . | IFN-γ (pg/mL) . | . | |
|---|---|---|---|---|
| Patient . | Proliferation in response to MVA-TRICOM . | Uninfected . | MVA-TRICOM . | |
| 8 | High | 0.0 | 748.2 | |
| 7 | High | 43.8 | 332.8 | |
| 11 | High | 37.4 | 220.8 | |
| 16 | High | 12.9 | 80.8 | |
| 18 | Low | 41.6 | 50.2 | |
| 14 | Intermediate | 0.0 | 0.0 | |
| 10 | Low | 0.0 | 0.0 | |
. | . | IFN-γ (pg/mL) . | . | |
|---|---|---|---|---|
| Patient . | Proliferation in response to MVA-TRICOM . | Uninfected . | MVA-TRICOM . | |
| 8 | High | 0.0 | 748.2 | |
| 7 | High | 43.8 | 332.8 | |
| 11 | High | 37.4 | 220.8 | |
| 16 | High | 12.9 | 80.8 | |
| 18 | Low | 41.6 | 50.2 | |
| 14 | Intermediate | 0.0 | 0.0 | |
| 10 | Low | 0.0 | 0.0 | |
CD3+ T cells from patients with CLL were stimulated (ratio of stimulator to effector cells, 1:2.5) with autologous CLL cells uninfected or infected with MVA-TRICOM. Supernatants were analyzed at 48 hours after stimulation.
IFN-γ indicates interferon γ.