Table 1.

Incidence of antibody and complement C3 deposition in kidney glomeruli




K4G4

L1B11

L3D10

mIgG
IgG   4/8*  4/8*  2/9   0/9  
C3
 
0/8
 
0/8
 
1/9
 
0/9
 



K4G4

L1B11

L3D10

mIgG
IgG   4/8*  4/8*  2/9   0/9  
C3
 
0/8
 
0/8
 
1/9
 
0/9
 

Frozen sections of kidney were analyzed after the mice were killed (ie, when the mice reached early removal criteria [tumors of 4000 m3]), with the exception of 2 mice in the L3D10-treated group, in whom tumors never met the criteria for early removal.

*

The incidence of IgG deposition in mice treated with K4G4 (P = .029) and L1B11 (P = .029), but not L3D10 (P = .47), is significantly higher than in the control group.

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