Laboratory characteristics of cases with priapism and controls in a population of patients with SCD, presented as age-adjusted means ± standard error
. | Case subjects; n = 273 . | Control subjects; n = 979 . | P . |
|---|---|---|---|
| Age at last follow-up, y ± SD | 26.2 ± 12.28 | 22.8 ± 12.72 | .001 |
| Systolic blood pressure | 110 ± 0.61 | 109 ± 0.32 | .327 |
| Diastolic blood pressure | 66 ± 0.47 | 66 ± 0.25 | .111 |
| Hemoglobin, g/dL | 8.64 ± 0.13 | 9.51 ± 0.07 | < .001 |
| HbF, g/dL | 0.44 ± 0.04 | 0.50 ± 0.02 | .309 |
| % of HbF | 5.19 ± 0.46 | 5.44 ± 0.24 | .619 |
| Creatinine, mg/dL | 0.74 ± 0.10 | 0.84 ± 0.05 | .419 |
| Bilirubin, mg/dL | 3.52 ± 0.13 | 2.92 ± 0.07 | < .001 |
| Urea nitrogen (BUN), mg/dL | 9.49 ± 0.39 | 10.09 ± 0.20 | .178 |
| Packed cell volume | 25.38 ± 0.36 | 28.03 ± 0.19 | < .001 |
| Mean corpuscular volume, μm3 | 89.82 ± 0.48 | 87.18 ± 0.25 | < .001 |
| LDH, units/L | 526.19 ± 13.08 | 459.23 ± 6.92 | < .001 |
| Platelet count, per mL | 425.66 ± 7.61 | 385.16 ± 4.04 | < .001 |
| RBC count, million/mm3 | 2.86 ± 0.05 | 3.26 ± 0.03 | < .001 |
| Reticulocytes | 11.67 ± 0.35 | 9.37 ± 0.18 | < .001 |
| AST, units/L | 50.34 ± 1.44 | 45.78 ± 0.76 | .005 |
| ALT, units/L | 36.70 ± 2.96 | 35.18 ± 1.55 | .649 |
| WBC count, × 109/L | 11.62 ± 0.20 | 10.18 ± 0.10 | < .0001 |
. | Case subjects; n = 273 . | Control subjects; n = 979 . | P . |
|---|---|---|---|
| Age at last follow-up, y ± SD | 26.2 ± 12.28 | 22.8 ± 12.72 | .001 |
| Systolic blood pressure | 110 ± 0.61 | 109 ± 0.32 | .327 |
| Diastolic blood pressure | 66 ± 0.47 | 66 ± 0.25 | .111 |
| Hemoglobin, g/dL | 8.64 ± 0.13 | 9.51 ± 0.07 | < .001 |
| HbF, g/dL | 0.44 ± 0.04 | 0.50 ± 0.02 | .309 |
| % of HbF | 5.19 ± 0.46 | 5.44 ± 0.24 | .619 |
| Creatinine, mg/dL | 0.74 ± 0.10 | 0.84 ± 0.05 | .419 |
| Bilirubin, mg/dL | 3.52 ± 0.13 | 2.92 ± 0.07 | < .001 |
| Urea nitrogen (BUN), mg/dL | 9.49 ± 0.39 | 10.09 ± 0.20 | .178 |
| Packed cell volume | 25.38 ± 0.36 | 28.03 ± 0.19 | < .001 |
| Mean corpuscular volume, μm3 | 89.82 ± 0.48 | 87.18 ± 0.25 | < .001 |
| LDH, units/L | 526.19 ± 13.08 | 459.23 ± 6.92 | < .001 |
| Platelet count, per mL | 425.66 ± 7.61 | 385.16 ± 4.04 | < .001 |
| RBC count, million/mm3 | 2.86 ± 0.05 | 3.26 ± 0.03 | < .001 |
| Reticulocytes | 11.67 ± 0.35 | 9.37 ± 0.18 | < .001 |
| AST, units/L | 50.34 ± 1.44 | 45.78 ± 0.76 | .005 |
| ALT, units/L | 36.70 ± 2.96 | 35.18 ± 1.55 | .649 |
| WBC count, × 109/L | 11.62 ± 0.20 | 10.18 ± 0.10 | < .0001 |
With the exception of age at last follow-up (presented as mean ± SD), the means shown in the table are age-adjusted and presented as mean ± standard error.
HbF indicates fetal hemoglobin; BUN, blood urea nitrogen; LDH, lactic dehydrogenase; RBC, red blood cell; AST, aspartate aminotransferase; ALT, alanine aminotransferase; and WBC, white blood cell.