Table 2.

Main features of the 14 patients with HIT






Previous heparin exposure









Patient no.
Age, y
Sex
Cancer present
Previous exposure
Time since exposure
Setting
Drug
Dosage
Time to HIT, d
Platelet count, × 109/L, baseline/nadir
IgG ELISA OD
HIPA
TE
Time to TE d
1   73   M   Yes   Yes   4 mo   In hospital   Nadroparin   High   5   259/127   0.8   Negative   No   NA  
2   26   M   Yes   No   NA   In hospital   Nadroparin   High   7   249/18   1.3   Positive   No   NA  
3   74   M   No   Yes   2 y   In hospital   Nadroparin   High   12   150/32   >2.0   Positive   TIA   14  
4   84   F   Yes   Yes   5 wk   In hospital   Enoxaparin   High   2   231/83   >2.0   Positive   No   NA  
5   83   F   No   Yes   5 mo   In hospital   Dalteparin   Low   5   209/68   1.8   Positive   No   NA  
6   73   M   Yes   Yes   6 mo   In hospital   Nadroparin   Intermediate   9   210/70   >2.0   Positive   Ischemic stroke   12  
7   83   M   No   No   NA   In hospital   Nadroparin   Low   12   214/30   1.1   Positive   No   NA  
8   63   M   No   Yes   5 mo   At home   Dalteparin   Low   5   186/50   0.9   Negative   No   NA  
9   22   M   No   Yes   12 mo   At home   Enoxaparin   Intermediate   9   232/68   1.4   Positive   DVT   11  
10   23   M   No   No   NA   At home   Nadroparin   Intermediate   9   248/65   1.2   Positive   No   NA  
11   65   F   No   Yes   4 mo   At home   Enoxaparin   Intermediate   4   313/67   1.0   Positive   No   NA  
12   44   F   No   Yes   8 mo   At home   Nadroparin   High   6   365/124   1.0   Negative   No   NA  
13   38   M   No   No   NA   At home   Nadroparin   Intermediate   13   234/90   1.2   Positive   No   NA  
14
 
72
 
F
 
No
 
Yes
 
6 mo
 
At home
 
Nadroparin
 
High
 
5
 
255/88
 
>2.0
 
Positive
 
Extension of DVT
 
6
 





Previous heparin exposure









Patient no.
Age, y
Sex
Cancer present
Previous exposure
Time since exposure
Setting
Drug
Dosage
Time to HIT, d
Platelet count, × 109/L, baseline/nadir
IgG ELISA OD
HIPA
TE
Time to TE d
1   73   M   Yes   Yes   4 mo   In hospital   Nadroparin   High   5   259/127   0.8   Negative   No   NA  
2   26   M   Yes   No   NA   In hospital   Nadroparin   High   7   249/18   1.3   Positive   No   NA  
3   74   M   No   Yes   2 y   In hospital   Nadroparin   High   12   150/32   >2.0   Positive   TIA   14  
4   84   F   Yes   Yes   5 wk   In hospital   Enoxaparin   High   2   231/83   >2.0   Positive   No   NA  
5   83   F   No   Yes   5 mo   In hospital   Dalteparin   Low   5   209/68   1.8   Positive   No   NA  
6   73   M   Yes   Yes   6 mo   In hospital   Nadroparin   Intermediate   9   210/70   >2.0   Positive   Ischemic stroke   12  
7   83   M   No   No   NA   In hospital   Nadroparin   Low   12   214/30   1.1   Positive   No   NA  
8   63   M   No   Yes   5 mo   At home   Dalteparin   Low   5   186/50   0.9   Negative   No   NA  
9   22   M   No   Yes   12 mo   At home   Enoxaparin   Intermediate   9   232/68   1.4   Positive   DVT   11  
10   23   M   No   No   NA   At home   Nadroparin   Intermediate   9   248/65   1.2   Positive   No   NA  
11   65   F   No   Yes   4 mo   At home   Enoxaparin   Intermediate   4   313/67   1.0   Positive   No   NA  
12   44   F   No   Yes   8 mo   At home   Nadroparin   High   6   365/124   1.0   Negative   No   NA  
13   38   M   No   No   NA   At home   Nadroparin   Intermediate   13   234/90   1.2   Positive   No   NA  
14
 
72
 
F
 
No
 
Yes
 
6 mo
 
At home
 
Nadroparin
 
High
 
5
 
255/88
 
>2.0
 
Positive
 
Extension of DVT
 
6
 

ELISA indicates enzyme-linked immunosorbent assay; TE, thromboembolism; TIA, transitory ischemic attack; NA, not applicable.

Close Modal

or Create an Account

Close Modal
Close Modal