Table 2.

Presence of EBNA1- and BZLF1-specific memory T cells




NHL present early*

Detectable till end of follow-up

CD4 at time of loss

Progressor present early*

Detectable till end of follow-up

CD4 at time of loss

Slow progressor present early*

Detectable till end of follow-up

CD4 at time of loss
EBNA1-CD4   7/9   0/7   300   4/4   2/4   290   4/4   1/4   280  
BZLF1-CD4   4/8   1/4   310   3/3   2/3   290   4/4   1/4   360  
EBNA1-CD8   4/9   2/4   385   3/4   2/3   280   3/4   2/3   280  
BZLF1-CD8
 
6/8
 
6/6
 
ND
 
3/4
 
3/3
 
ND
 
3/4
 
2/3
 
280
 



NHL present early*

Detectable till end of follow-up

CD4 at time of loss

Progressor present early*

Detectable till end of follow-up

CD4 at time of loss

Slow progressor present early*

Detectable till end of follow-up

CD4 at time of loss
EBNA1-CD4   7/9   0/7   300   4/4   2/4   290   4/4   1/4   280  
BZLF1-CD4   4/8   1/4   310   3/3   2/3   290   4/4   1/4   360  
EBNA1-CD8   4/9   2/4   385   3/4   2/3   280   3/4   2/3   280  
BZLF1-CD8
 
6/8
 
6/6
 
ND
 
3/4
 
3/3
 
ND
 
3/4
 
2/3
 
280
 

ND indicates not done.

*

Frequency of individuals in whom these responses were measurable at an early time point during HIV/total number of individuals tested

Frequency of individuals in whom these responses were maintained until end of follow-up/total individuals tested

Total CD4+ T-cell numbers per μL at time point when memory T-cell responses were lost

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