Presence of EBNA1- and BZLF1-specific memory T cells
. | NHL present early* . | Detectable till end of follow-up† . | CD4 at time of loss‡ . | Progressor present early* . | Detectable till end of follow-up† . | CD4 at time of loss‡ . | Slow progressor present early* . | Detectable till end of follow-up† . | CD4 at time of loss‡ . |
---|---|---|---|---|---|---|---|---|---|
EBNA1-CD4 | 7/9 | 0/7 | 300 | 4/4 | 2/4 | 290 | 4/4 | 1/4 | 280 |
BZLF1-CD4 | 4/8 | 1/4 | 310 | 3/3 | 2/3 | 290 | 4/4 | 1/4 | 360 |
EBNA1-CD8 | 4/9 | 2/4 | 385 | 3/4 | 2/3 | 280 | 3/4 | 2/3 | 280 |
BZLF1-CD8 | 6/8 | 6/6 | ND | 3/4 | 3/3 | ND | 3/4 | 2/3 | 280 |
. | NHL present early* . | Detectable till end of follow-up† . | CD4 at time of loss‡ . | Progressor present early* . | Detectable till end of follow-up† . | CD4 at time of loss‡ . | Slow progressor present early* . | Detectable till end of follow-up† . | CD4 at time of loss‡ . |
---|---|---|---|---|---|---|---|---|---|
EBNA1-CD4 | 7/9 | 0/7 | 300 | 4/4 | 2/4 | 290 | 4/4 | 1/4 | 280 |
BZLF1-CD4 | 4/8 | 1/4 | 310 | 3/3 | 2/3 | 290 | 4/4 | 1/4 | 360 |
EBNA1-CD8 | 4/9 | 2/4 | 385 | 3/4 | 2/3 | 280 | 3/4 | 2/3 | 280 |
BZLF1-CD8 | 6/8 | 6/6 | ND | 3/4 | 3/3 | ND | 3/4 | 2/3 | 280 |
ND indicates not done.
Frequency of individuals in whom these responses were measurable at an early time point during HIV/total number of individuals tested
Frequency of individuals in whom these responses were maintained until end of follow-up/total individuals tested
Total CD4+ T-cell numbers per μL at time point when memory T-cell responses were lost