Off-rate (k0) and transition-state distance (γ) of the A:a interactions measured using fibrin(ogen) molecules and their fragments
Interacting molecular pairs . | k0 (s-1) . | γ (nm) . |
|---|---|---|
| desA-fibrin/fibrinogen | 0.00067 ± 0.00063 | 0.34 ± 0.03 |
| desA-NDSK/fibrinogen | 0.00086 ± 0.00059 | 0.33 ± 0.06 |
| desA-NDSK/fragment D | 0.00089 ± 0.00037 | 0.33 ± 0.05 |
| desAB-fibrin/fibrinogen | 0.00098 ± 0.00060 | 0.29 ± 0.04 |
| desAB-NDSK/fibrinogen | 0.00135 ± 0.00072 | 0.33 ± 0.02 |
| desAB-NDSK/fragment D | 0.00034 ± 0.00052 | 0.37 ± 0.05 |
Interacting molecular pairs . | k0 (s-1) . | γ (nm) . |
|---|---|---|
| desA-fibrin/fibrinogen | 0.00067 ± 0.00063 | 0.34 ± 0.03 |
| desA-NDSK/fibrinogen | 0.00086 ± 0.00059 | 0.33 ± 0.06 |
| desA-NDSK/fragment D | 0.00089 ± 0.00037 | 0.33 ± 0.05 |
| desAB-fibrin/fibrinogen | 0.00098 ± 0.00060 | 0.29 ± 0.04 |
| desAB-NDSK/fibrinogen | 0.00135 ± 0.00072 | 0.33 ± 0.02 |
| desAB-NDSK/fragment D | 0.00034 ± 0.00052 | 0.37 ± 0.05 |
Data are expressed as mean ± standard error of the mean.