Table 7.

Comparisons between the HCT-CI and the CCI in the validation set (n = 347) for events within first 2 years




HCT-CI for 3 risk groups

CCI for 3 risk groups

P*
Nonrelapse mortality    
c-statistic (SE*), overall   0.649 (0.029)   0.520 (0.019)   < .001  
c-statistic (SE*), yes/no 2 y   0.685 (0.037)   0.532 (0.023)   < .001  
c-statistic (SE*), yes/no 1 y   0.692 (0.036)   0.546 (0.025)   < .001  
Likelihood ratio   26.6   1.2   
Adjusted likelihood ratio  21.4   0.7   
Overall survival    
c-statistic (SE*), overall   0.624 (0.021)   0.536 (0.015)   < .001  
c-statistic (SE*), yes/no 2 y   0.657 (0.031)   0.548 (0.019)   < .001  
c-statistic (SE*), yes/no 1 y   0.661 (0.030)   0.561 (0.021)   < .001  
Likelihood ratio   31.8   7.6   
Adjusted likelihood ratio
 
23.7
 
7.1
 

 



HCT-CI for 3 risk groups

CCI for 3 risk groups

P*
Nonrelapse mortality    
c-statistic (SE*), overall   0.649 (0.029)   0.520 (0.019)   < .001  
c-statistic (SE*), yes/no 2 y   0.685 (0.037)   0.532 (0.023)   < .001  
c-statistic (SE*), yes/no 1 y   0.692 (0.036)   0.546 (0.025)   < .001  
Likelihood ratio   26.6   1.2   
Adjusted likelihood ratio  21.4   0.7   
Overall survival    
c-statistic (SE*), overall   0.624 (0.021)   0.536 (0.015)   < .001  
c-statistic (SE*), yes/no 2 y   0.657 (0.031)   0.548 (0.019)   < .001  
c-statistic (SE*), yes/no 1 y   0.661 (0.030)   0.561 (0.021)   < .001  
Likelihood ratio   31.8   7.6   
Adjusted likelihood ratio
 
23.7
 
7.1
 

 
*

Estimated from 100 bootstrap samples

Adjusted for age, disease risk, and conditioning.

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