Table 1. Analysis of chemokine... | American Society of Hematology

Table 1.

Analysis of chemokine production by epithelial cell monolayers incubated with the indicated bacterial strains

Bacterial strains^*	CXCL8, ng/mL	IL-10, ng/mL	CCL20, ng/mL	CCL22, ng/mL	CCL18, ng/mL	CCL19, ng/mL	CCL2, ng/mL	CCL17, ng/mL	Invasive	Flagellin
SL 1344 WT	1.55	< DL	0.96	< DL	17.0	< DL	< DL	< DL	Yes	Yes
htrA	1.13	—	1.08	—	—	< DL	—	—	Yes	Yes
ssaV (SPI-II)	1.31	—	1.13	<DL	—	< DL	—	—	Yes	Yes
ompCompF	0.72	—	0.65	—	—	< DL	—	—	Yes	Yes
SL-FliC	< DL	< DL	0.10	< DL	22.8	—	< DL	< DL	Yes	No
msbB	0.07	—	0.46	—	—	< DL	—	—	No	Yes
SurA	0.56	—	1.02	—	—	< DL	—	—	No	Yes
SL-InvA (SPI-I)	0.16	< DL	0.88	< DL	7.8	< DL	< DL	< DL	No	Yes
BS	< DL	—	1.10	—	—	—	—	—	No	Yes
LP	< DL	< DL	0.12	< DL	8.1	—	< DL	< DL	No	No
DH5α	< DL	—	0.08	—	—	—	—	—	No	No
Untreated	< DL	< DL	0.04	< DL	8.2	< DL	< DL	< DL	—	—

Bacterial strains^*	CXCL8, ng/mL	IL-10, ng/mL	CCL20, ng/mL	CCL22, ng/mL	CCL18, ng/mL	CCL19, ng/mL	CCL2, ng/mL	CCL17, ng/mL	Invasive	Flagellin
SL 1344 WT	1.55	< DL	0.96	< DL	17.0	< DL	< DL	< DL	Yes	Yes
htrA	1.13	—	1.08	—	—	< DL	—	—	Yes	Yes
ssaV (SPI-II)	1.31	—	1.13	<DL	—	< DL	—	—	Yes	Yes
ompCompF	0.72	—	0.65	—	—	< DL	—	—	Yes	Yes
SL-FliC	< DL	< DL	0.10	< DL	22.8	—	< DL	< DL	Yes	No
msbB	0.07	—	0.46	—	—	< DL	—	—	No	Yes
SurA	0.56	—	1.02	—	—	< DL	—	—	No	Yes
SL-InvA (SPI-I)	0.16	< DL	0.88	< DL	7.8	< DL	< DL	< DL	No	Yes
BS	< DL	—	1.10	—	—	—	—	—	No	Yes
LP	< DL	< DL	0.12	< DL	8.1	—	< DL	< DL	No	No
DH5α	< DL	—	0.08	—	—	—	—	—	No	No
Untreated	< DL	< DL	0.04	< DL	8.2	< DL	< DL	< DL	—	—

The following cytokines were below the detection limit in culture supernatants from any conditions: CCL3, CXCL 12.

Bacterial strains: Invasive S typhimurium: wild type, SL 1344 WT; htrA; SPI-II (ssaV), ompComp, FliC. Noninvasive S typhimurium: msbB (lipid A mutant); SurA; SPI-I (InvA); E. coli: DH5α; B. subtilis: BS; L plantarum: LP.

< DL indicates below detection limit; —, not determined.

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