Table 2. Evolution over time of... | American Society of Hematology

Table 2.

Evolution over time of parvovirus B19 markers in case 1

Sample date	No. mo. of follow-up	B19 IgM, S/CO^*	B19 IgG, S/CO	VP1 PCR, × 1†	NS1 PCR, × 5	QPCR, × 2	Viral load, IU/mL‡
1998, 03 Apr	—	−	−	−	NA	NA	NA
2001
25 Jan	—	−	−	+	NA	NA	NA
08 Feb	0	9.9	6.5	+	+++++	++	12 850
28 Feb	1	11.0	7.5	+	+++++	++	3 155
26 Mar	2	6.8	7.7	+	+++++	++	1 545
02 May	3	2.8	8.0	+	+++++	++	1 285
29 May	4	1.9	8.8	+	+++++	++	205
04 Oct	8	−	9.3	+	+++−−	++	77
05 Nov	9	−	8.4	+	+++−−	++	50
21 Nov	10	−	8.6	−	+++−−	−−	0
26 Dec	11	−	8.6	−	+++−−	++	22
2002
28 Jan	12	−	10.0	−	++−−−	+−	51
06 Mar	14	−	7.5	+	+−−−−	++	67
08 Apr	15	−	8.4	−	+−−−−	++	12
13 May	16	−	8.0	−	+−−−−	−−	0
11 Jun	17	−	9.2	−	++−−−	−−	0
09 Dec	23	−	7.4	−	−−−−−	++	30
2003
20 Jan	24	−	7.8	−	−−−−−	++	8
20 Mar	26	−	7.5	−	−−−−−	++	10
18 Apr	27	−	8.0	−	−−−−−	+−	5
20 Jun	29	−	7.2	−	−−−−−	+−	2
11 Jul	30	−	7.5	−	+−−−−	++	16
25 Aug	31	−	7.5	−	−−−−−	++	37
26 Sep	32	−	6.8	−	−−−−−	+−	20
24 Nov	34	−	7.4	−	−−−−−	+−	21
22 Dec	35	−	7.3	−	−−−−−	+−	9
2004
20 Feb	37	−	7.7	−	−−−−−	+−	30
15 Mar	38	−	7.0	−	+−−−−	−−	0
15 Apr	39	−	7.8	−	−−−−−	++	12

Sample date	No. mo. of follow-up	B19 IgM, S/CO^*	B19 IgG, S/CO	VP1 PCR, × 1†	NS1 PCR, × 5	QPCR, × 2	Viral load, IU/mL‡
1998, 03 Apr	—	−	−	−	NA	NA	NA
2001
25 Jan	—	−	−	+	NA	NA	NA
08 Feb	0	9.9	6.5	+	+++++	++	12 850
28 Feb	1	11.0	7.5	+	+++++	++	3 155
26 Mar	2	6.8	7.7	+	+++++	++	1 545
02 May	3	2.8	8.0	+	+++++	++	1 285
29 May	4	1.9	8.8	+	+++++	++	205
04 Oct	8	−	9.3	+	+++−−	++	77
05 Nov	9	−	8.4	+	+++−−	++	50
21 Nov	10	−	8.6	−	+++−−	−−	0
26 Dec	11	−	8.6	−	+++−−	++	22
2002
28 Jan	12	−	10.0	−	++−−−	+−	51
06 Mar	14	−	7.5	+	+−−−−	++	67
08 Apr	15	−	8.4	−	+−−−−	++	12
13 May	16	−	8.0	−	+−−−−	−−	0
11 Jun	17	−	9.2	−	++−−−	−−	0
09 Dec	23	−	7.4	−	−−−−−	++	30
2003
20 Jan	24	−	7.8	−	−−−−−	++	8
20 Mar	26	−	7.5	−	−−−−−	++	10
18 Apr	27	−	8.0	−	−−−−−	+−	5
20 Jun	29	−	7.2	−	−−−−−	+−	2
11 Jul	30	−	7.5	−	+−−−−	++	16
25 Aug	31	−	7.5	−	−−−−−	++	37
26 Sep	32	−	6.8	−	−−−−−	+−	20
24 Nov	34	−	7.4	−	−−−−−	+−	21
22 Dec	35	−	7.3	−	−−−−−	+−	9
2004
20 Feb	37	−	7.7	−	−−−−−	+−	30
15 Mar	38	−	7.0	−	+−−−−	−−	0
15 Apr	39	−	7.8	−	−−−−−	++	12

— indicates not applicable (follow-up began with first sample tested after QPCR); −, negative result; NA, sample not available; +, positive result.

Sample to cut-off.

Number of replicates.

Viral load was calculated by QPCR¹⁹ as the mean of 2 duplicate values or a single value when only one replicate was positive.