Table 2.

Cellular composition in the lungs at 5 weeks after infection



Cells positive 5 weeks after infection, %
Cell type
WT
TMpro/pro
CD4+  48.4 ± 4.2   47.8 ± 2.2  
CD8+  37.3 ± 2.4   34.3 ± 2.1  
CD4+/CD69+  15.1 ± 1.2   17.8 ± 2.0  
CD4+/CD25+  2.3 ± 1.3   4.1 ± 2.1  
CD8+/CD69+  12.9 ± 6.2   10.1 ± 3.2  
CD8+/CD25+  4.9 ± 1.3   3.6 ± 1.4  
Gr-1+/CD11b+
 
22.9 ± 2.1
 
19.5 ± 1.8
 


Cells positive 5 weeks after infection, %
Cell type
WT
TMpro/pro
CD4+  48.4 ± 4.2   47.8 ± 2.2  
CD8+  37.3 ± 2.4   34.3 ± 2.1  
CD4+/CD69+  15.1 ± 1.2   17.8 ± 2.0  
CD4+/CD25+  2.3 ± 1.3   4.1 ± 2.1  
CD8+/CD69+  12.9 ± 6.2   10.1 ± 3.2  
CD8+/CD25+  4.9 ± 1.3   3.6 ± 1.4  
Gr-1+/CD11b+
 
22.9 ± 2.1
 
19.5 ± 1.8
 

Lymphocyte typing was performed on pulmonary cell suspensions 5 weeks after infection as described in “FACS analysis.” Data are mean ± SE of 8 mice per group. FACS results of the lymphocytes are expressed as the percentage of CD4+, CD8+, CD25+, and CD69+ population; results of neutrophils as percentage CD11b+ cells within the Gr-1+ population. Differences between groups were not significant.

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