Leukocyte counts in lung homogenates
. | 2 weeks after administration . | . | 5 weeks after administration . | . | ||
---|---|---|---|---|---|---|
. | WT . | TMpro/pro . | WT . | TMpro/pro . | ||
Total cells | 0.9 ± 0.7 | 1.0 ± 0.5 | 11.9 ± 1.5 | 16.1 ± 2.4 | ||
Neutrophils | 0.3 ± 0.7 | 0.7 ± 0.1* | 2.6 ± 0.7 | 12.4 ± 0.9* | ||
Macrophages | 0.2 ± 0.9 | 0.2 ± 0.2 | 5.3 ± 0.3 | 2.2 ± 0.3* | ||
Lymphocytes | 0.3 ± 0.1 | 0.1 ± 0.2 | 4.0 ± 0.8 | 1.5 ± 1.2* |
. | 2 weeks after administration . | . | 5 weeks after administration . | . | ||
---|---|---|---|---|---|---|
. | WT . | TMpro/pro . | WT . | TMpro/pro . | ||
Total cells | 0.9 ± 0.7 | 1.0 ± 0.5 | 11.9 ± 1.5 | 16.1 ± 2.4 | ||
Neutrophils | 0.3 ± 0.7 | 0.7 ± 0.1* | 2.6 ± 0.7 | 12.4 ± 0.9* | ||
Macrophages | 0.2 ± 0.9 | 0.2 ± 0.2 | 5.3 ± 0.3 | 2.2 ± 0.3* | ||
Lymphocytes | 0.3 ± 0.1 | 0.1 ± 0.2 | 4.0 ± 0.8 | 1.5 ± 1.2* |
Data are mean numbers of cells × 109/L, ± SE (n = 8 mice per group for each time point) at 2 and 5 weeks after intranasal administration of M tuberculosis (105 CFUs). *P < .05 versus WT mice.