Table 2.

Hematologic parameters of Irp2−/−versus wild-type mice



Males (n)

Females (n)

+/+
−/−
+/+
−/−
RBC count, 1012/L   8.43 ± 0.25 (11)   7.96 ± 0.20 (7)   7.53 ± 0.23 (14)   7.27 ± 0.15 (18)  
MCV, fL   53.04 ± 0.57 (10)   46.78 ± 0.75 (7)  51.11 ± 0.58 (12)   47.21 ± 0.52 (17) 
Hematocrit level, L/L   0.45 ± 0.01 (11)   0.37 ± 0.01 (7)  0.39 ± 0.01 (14)   0.34 ± 0.01 (18)* 
Hemoglobin level, g/L   138 ± 3 (11)   115 ± 3 (7)  128 ± 6 (14)   108 ± 3 (18)* 
Thrombocyte count, 109/L   613 ± 28 (8)   761 ± 56 (6)   555 ± 44 (9)   611 ± 65 (9)  
Reticulocyte count, 109/L   148.0 ± 12.8 (11)   194.2 ± 35.6 (6)   354.4 ± 100.4 (7)   347.4 ± 121.5 (9)  
WBC count, 109/L   6.318 ± 0.643 (11)   6.985 ± 0.883 (7)   5.036 ± 0.414 (14)   5.322 ± 0.396 (18)  
Neutrophil count, 109/L   0.725 ± 0.093 (7)   0.937 ± 0.213 (6)   0.716 ± 0.228 (9)   0.454 ± 0.052 (9)  
Lymphocyte count, 109/L   5.601 ± 0.834 (7)   5.157 ± 0.682 (6)   4.115 ± 0.444 (9)   5.038 ± 0.461 (9)  
Monocyte count, 109/L
 
0.121 ± 0.024 (7)
 
0.128 ± 0.044 (6)
 
0.266 ± 0.188 (9)
 
0.252 ± 0.195 (9)
 


Males (n)

Females (n)

+/+
−/−
+/+
−/−
RBC count, 1012/L   8.43 ± 0.25 (11)   7.96 ± 0.20 (7)   7.53 ± 0.23 (14)   7.27 ± 0.15 (18)  
MCV, fL   53.04 ± 0.57 (10)   46.78 ± 0.75 (7)  51.11 ± 0.58 (12)   47.21 ± 0.52 (17) 
Hematocrit level, L/L   0.45 ± 0.01 (11)   0.37 ± 0.01 (7)  0.39 ± 0.01 (14)   0.34 ± 0.01 (18)* 
Hemoglobin level, g/L   138 ± 3 (11)   115 ± 3 (7)  128 ± 6 (14)   108 ± 3 (18)* 
Thrombocyte count, 109/L   613 ± 28 (8)   761 ± 56 (6)   555 ± 44 (9)   611 ± 65 (9)  
Reticulocyte count, 109/L   148.0 ± 12.8 (11)   194.2 ± 35.6 (6)   354.4 ± 100.4 (7)   347.4 ± 121.5 (9)  
WBC count, 109/L   6.318 ± 0.643 (11)   6.985 ± 0.883 (7)   5.036 ± 0.414 (14)   5.322 ± 0.396 (18)  
Neutrophil count, 109/L   0.725 ± 0.093 (7)   0.937 ± 0.213 (6)   0.716 ± 0.228 (9)   0.454 ± 0.052 (9)  
Lymphocyte count, 109/L   5.601 ± 0.834 (7)   5.157 ± 0.682 (6)   4.115 ± 0.444 (9)   5.038 ± 0.461 (9)  
Monocyte count, 109/L
 
0.121 ± 0.024 (7)
 
0.128 ± 0.044 (6)
 
0.266 ± 0.188 (9)
 
0.252 ± 0.195 (9)
 

Results were obtained from 8- to 10-week-old mice and are given ± standard errors. The sample size (n) is indicated. RBC indicates red blood cell; MCV, mean corpuscular volume; and WBC, white blood cell.

*

P = .01, Student t test.

P = .001, Student t test.

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