Table 2.

Subject demographics by response to 0.4 μM epinephrine, PR study


Subject characteristic

Less than 60% aggregation

At least 60% aggregation

P
Mean age, y, ± SD   34.3 ± 10.6   33.5 ± 9.1   .619  
% women   64.0   81.6   .015  
Race, % of group    .179  
    African-American   37.3   55.0   
    White   37.3   30.6   
    Hispanic   16.9   10.2   
    Asian   7.1   4.1   
    Other   1.3   0.0   
Mean body mass index, kg/m2, ± SD   26.6 ± 5.8   27.3 ± 6.2   .442  
Women using oral contraceptives, %   25.4   22.5   .701  
Premenopausal women, %   81.2   85   .794  
Premenopausal women in luteal phase, %   54.9   71.4   .107  
Current smokers, %   12.4   8.2   .396  
Subjects with hypertension, %   5.9   0   .081  
Mean fibrinogen, mg/dL*, ± SD
 
324 ± 91
 
364 ± 110
 
.011
 

Subject characteristic

Less than 60% aggregation

At least 60% aggregation

P
Mean age, y, ± SD   34.3 ± 10.6   33.5 ± 9.1   .619  
% women   64.0   81.6   .015  
Race, % of group    .179  
    African-American   37.3   55.0   
    White   37.3   30.6   
    Hispanic   16.9   10.2   
    Asian   7.1   4.1   
    Other   1.3   0.0   
Mean body mass index, kg/m2, ± SD   26.6 ± 5.8   27.3 ± 6.2   .442  
Women using oral contraceptives, %   25.4   22.5   .701  
Premenopausal women, %   81.2   85   .794  
Premenopausal women in luteal phase, %   54.9   71.4   .107  
Current smokers, %   12.4   8.2   .396  
Subjects with hypertension, %   5.9   0   .081  
Mean fibrinogen, mg/dL*, ± SD
 
324 ± 91
 
364 ± 110
 
.011
 

For subjects with less than 60% aggregation, n = 310; for those with at least 60% aggregation, n = 49. No subjects had diabetes.

*

For logistical reasons, assays were performed on the first 308 subjects, 266 with less than 60% aggregation and 42 with at least 60% aggregation.

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