Table 1.

Characterization of the IgG fractions and clinical data of the patients from whom the IgG was obtained




Pt A

Pt B

Pt C

Pt D

Pt E

Pt F
Diagnosis   PAPS   PAPS   SLE-APS   SLE-APS   PAPS   PAPS  
Arterial thrombosis   +   +   +   +   –   +  
Venous thrombosis   +   +   –   –   +   +  
Fetal loss   –   +   +   –   +   –  
GPL, U   66   72   74   67   141   117  
IgG anti-β2GPI, OD values, 405 nm   1.67   1.25   1.38   2.91   2.02   0.9  
Human C1q binding, OD values, 405 nm
 
0.89
 
0.87
 
0.88
 
1.20
 
0.98
 
0.96
 



Pt A

Pt B

Pt C

Pt D

Pt E

Pt F
Diagnosis   PAPS   PAPS   SLE-APS   SLE-APS   PAPS   PAPS  
Arterial thrombosis   +   +   +   +   –   +  
Venous thrombosis   +   +   –   –   +   +  
Fetal loss   –   +   +   –   +   –  
GPL, U   66   72   74   67   141   117  
IgG anti-β2GPI, OD values, 405 nm   1.67   1.25   1.38   2.91   2.02   0.9  
Human C1q binding, OD values, 405 nm
 
0.89
 
0.87
 
0.88
 
1.20
 
0.98
 
0.96
 

Pt indicates patient; PAPS, primary APS; SLE-APS, systemic lupus erythematosus–associated APS; GPL, IgG antiphospholipid; OD, optical density.

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