Table 3.

Dynamics of elimination of autologus infected MDM and CD8+ cell infiltration in brains of 1-MT mice versus control mice


Treatment group, by week*

Macrophages per section

HIV-1 p24+ macrophages, %

Iba1 area per section, %

CD8+ T lymphocytes per section
Week 2     
   Control   70.83 ± 35.98   32.0 ± 9.0   3.95 ± 0.46   298.0 ± 91.22  
   1-MT   68.66 ± 23.36   42.0 ± 10.77   4.65 ± 0.63   597.0 ± 109.76 
Week 3     
   Control   44.2 ± 25.97   53.0 ± 2.51   4.52 ± 0.87   193.0 ± 106.65  
   1-MT
 
9.0 ± 4.65
 
53.0 ± 11.32
 
5.07 ± 0.44
 
256.0 ± 45.6
 

Treatment group, by week*

Macrophages per section

HIV-1 p24+ macrophages, %

Iba1 area per section, %

CD8+ T lymphocytes per section
Week 2     
   Control   70.83 ± 35.98   32.0 ± 9.0   3.95 ± 0.46   298.0 ± 91.22  
   1-MT   68.66 ± 23.36   42.0 ± 10.77   4.65 ± 0.63   597.0 ± 109.76 
Week 3     
   Control   44.2 ± 25.97   53.0 ± 2.51   4.52 ± 0.87   193.0 ± 106.65  
   1-MT
 
9.0 ± 4.65
 
53.0 ± 11.32
 
5.07 ± 0.44
 
256.0 ± 45.6
 

All values in table are mean ± SEM per 5-μm sections; 3 to 7 sections per mouse were analyzed.

*

Days after MDM injection

P < .03, compared with control

P = .07, compared with control

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