Table 2.

Human cells and plasma levels of HIV-1 p24 in peripheral blood of hu-PBL-NOD/SCID mice with HIVE


Treatment group, by week*

Lymphocyte population, %

HIV-1 p24, mean pg/mL ± SEM
CD3+
CD4+
CD8+
Week 1     
   Control   33.33   16.22   14.97   5.26 ± 3.25  
   1-MT   46.36  19.56   22.25§  1.76 ± 0.66  
Week 2     
   Control   51.76   20.38   26.91   198.0 ± 22.5  
   1-MT   39.80  17.92   19.63  103.0 ± 18.3 
Week 3     
   Control   44.48   21.78   21.10   320.0 ± 48.3  
   1-MT
 
33.12
 
16.64
 
15.07
 
328.0 ± 63.22
 

Treatment group, by week*

Lymphocyte population, %

HIV-1 p24, mean pg/mL ± SEM
CD3+
CD4+
CD8+
Week 1     
   Control   33.33   16.22   14.97   5.26 ± 3.25  
   1-MT   46.36  19.56   22.25§  1.76 ± 0.66  
Week 2     
   Control   51.76   20.38   26.91   198.0 ± 22.5  
   1-MT   39.80  17.92   19.63  103.0 ± 18.3 
Week 3     
   Control   44.48   21.78   21.10   320.0 ± 48.3  
   1-MT
 
33.12
 
16.64
 
15.07
 
328.0 ± 63.22
 
*

Days after MDM injection

No significant difference in percentage of CD4+ cells between the groups

P < .05, compared with control

§

P < .001, compared with control

P < .02, compared with control

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