Table 2.

Degree of engraftment of donor macrophages in the livers of recipient mice after BMT


Donor → recipient

n

GFP+F4/80+ donor macrophages, %

GFPF4/80+ host macrophages, %
GFP+wt → wt   4   35 ± 3   65 ± 3  
GFP+Hfe−/− → wt   4   37 ± 2   63 ± 2  
GFP+Hfe−/−Hfe−/−  4   33 ± 3   67 ± 3  
GFP+wt → Hfe−/−
 
4
 
36 ± 4
 
64 ± 4
 

Donor → recipient

n

GFP+F4/80+ donor macrophages, %

GFPF4/80+ host macrophages, %
GFP+wt → wt   4   35 ± 3   65 ± 3  
GFP+Hfe−/− → wt   4   37 ± 2   63 ± 2  
GFP+Hfe−/−Hfe−/−  4   33 ± 3   67 ± 3  
GFP+wt → Hfe−/−
 
4
 
36 ± 4
 
64 ± 4
 

Liver NPC fractions from mice that underwent BMT were analyzed by flow cytometry for the presence of GFP+ donor-derived macrophages. NPCs were stained for the macrophage marker F4/80, and the percentage of GFP+ and GFP within all F4/80+ cells is shown. Data are presented as mean ± SD.

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