Degree of engraftment of donor macrophages in the livers of recipient mice after BMT
Donor → recipient . | n . | GFP+F4/80+ donor macrophages, % . | GFP−F4/80+ host macrophages, % . |
---|---|---|---|
GFP+wt → wt | 4 | 35 ± 3 | 65 ± 3 |
GFP+Hfe−/− → wt | 4 | 37 ± 2 | 63 ± 2 |
GFP+Hfe−/− → Hfe−/− | 4 | 33 ± 3 | 67 ± 3 |
GFP+wt → Hfe−/− | 4 | 36 ± 4 | 64 ± 4 |
Donor → recipient . | n . | GFP+F4/80+ donor macrophages, % . | GFP−F4/80+ host macrophages, % . |
---|---|---|---|
GFP+wt → wt | 4 | 35 ± 3 | 65 ± 3 |
GFP+Hfe−/− → wt | 4 | 37 ± 2 | 63 ± 2 |
GFP+Hfe−/− → Hfe−/− | 4 | 33 ± 3 | 67 ± 3 |
GFP+wt → Hfe−/− | 4 | 36 ± 4 | 64 ± 4 |
Liver NPC fractions from mice that underwent BMT were analyzed by flow cytometry for the presence of GFP+ donor-derived macrophages. NPCs were stained for the macrophage marker F4/80, and the percentage of GFP+ and GFP− within all F4/80+ cells is shown. Data are presented as mean ± SD.