Table 2.

Autotaxin expression in EBV-positive and EBV-negative HL


Autotaxin status of HRS cells

EBV-positive

EBV-negative
Autotaxinhi  10   6  
Autotaxinneg/autotaxinlo  1   11  
Autotaxinhi, %
 
91 (10 of 11)
 
35 (6 of 17)
 

Autotaxin status of HRS cells

EBV-positive

EBV-negative
Autotaxinhi  10   6  
Autotaxinneg/autotaxinlo  1   11  
Autotaxinhi, %
 
91 (10 of 11)
 
35 (6 of 17)
 

HL cells were classified as autotaxinhi if autotaxin expression in HRS cells was equivalent to or higher than that observed in endothelial cells in the same section or as autotaxinneg/autotaxinlo if autotaxin expression in HRS cells was lower than in endothelial cells. Fisher exact test results show there was a significantly higher proportion of autotaxinhi tumors in the EBV-positive group (P = .006).

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