Table 1.

Differentially expressed genes in EBV-infected KM-H2 compared with control cells


Gene

Accession no.

Mean fold change

Ontology
ENPP2  L35594   4.16   Cell motility, GPCR protein signaling pathway  
CXCL12  U19495   4.12   Immune response, cell adhesion, chemotaxis, signal transduction  
GLUL  AL161952   3.33   Glutamine biosynthesis  
SERPINA6 NM_001756  3.10   Transport  
HMOX1 NM_002133  .2.87   Positive regulation of lkB kinase/NF-kB cascade  
CXCR4  AJ224869   2.80   Immune response, chemotaxis, GPCR protein signaling pathway  
CCL20 NM_004591  2.77   Immune response, chemotaxis, cell-cell signaling  
TPO  M17755   2.77   Thyroid hormone generation  
HSPA1A NM_005345  2.70   Ubiquitin-proteasome pathway, protein folding, signal transduction  
CYP1B1 NM_000104  2.55   Eye morphogenesis  
HAND1 NM_004821  2.55   Heart development, transcription from Pol II promoter  
GAGE1 NM_001472  −2.54   Cellular defense response  
OAS2 NM_016817  −2.60   Immune response  
FLJ20035 NM_017631  −2.62   Protein biosynthesis  
IFI44 NM_006417  −2.68   Viral response  
ZC3HDC1 NM_022750  −2.72   Nucleic acid binding  
ITIH5 NM_030569  −2.95   Regulation of localization, synthesis, and degradation of hyaluronan  
PTPRK NM_002844  −2.99   Transmembrane receptor protein tyrosine phosphatase activity  
CALD1  AL583520   −3.10   Muscle contraction and development  
PCP4 NM_006198  −3.41   Central nervous system development  
BCHE NM_000055  −3.50   Cocaine metabolism  
CXCL11  AF002985   −3.60   Immune response, chemotaxis, cell-cell signaling  
IFIT1 NM_001548  −3.75   Immune response  
KIAA0992 NM_016081  −3.90   Cell shape, adhesion, and contraction  
Clorf29 NM_006820  −6.01   Unknown  
IFI27
 
NM_005532
 
−19.38
 
Immune response
 

Gene

Accession no.

Mean fold change

Ontology
ENPP2  L35594   4.16   Cell motility, GPCR protein signaling pathway  
CXCL12  U19495   4.12   Immune response, cell adhesion, chemotaxis, signal transduction  
GLUL  AL161952   3.33   Glutamine biosynthesis  
SERPINA6 NM_001756  3.10   Transport  
HMOX1 NM_002133  .2.87   Positive regulation of lkB kinase/NF-kB cascade  
CXCR4  AJ224869   2.80   Immune response, chemotaxis, GPCR protein signaling pathway  
CCL20 NM_004591  2.77   Immune response, chemotaxis, cell-cell signaling  
TPO  M17755   2.77   Thyroid hormone generation  
HSPA1A NM_005345  2.70   Ubiquitin-proteasome pathway, protein folding, signal transduction  
CYP1B1 NM_000104  2.55   Eye morphogenesis  
HAND1 NM_004821  2.55   Heart development, transcription from Pol II promoter  
GAGE1 NM_001472  −2.54   Cellular defense response  
OAS2 NM_016817  −2.60   Immune response  
FLJ20035 NM_017631  −2.62   Protein biosynthesis  
IFI44 NM_006417  −2.68   Viral response  
ZC3HDC1 NM_022750  −2.72   Nucleic acid binding  
ITIH5 NM_030569  −2.95   Regulation of localization, synthesis, and degradation of hyaluronan  
PTPRK NM_002844  −2.99   Transmembrane receptor protein tyrosine phosphatase activity  
CALD1  AL583520   −3.10   Muscle contraction and development  
PCP4 NM_006198  −3.41   Central nervous system development  
BCHE NM_000055  −3.50   Cocaine metabolism  
CXCL11  AF002985   −3.60   Immune response, chemotaxis, cell-cell signaling  
IFIT1 NM_001548  −3.75   Immune response  
KIAA0992 NM_016081  −3.90   Cell shape, adhesion, and contraction  
Clorf29 NM_006820  −6.01   Unknown  
IFI27
 
NM_005532
 
−19.38
 
Immune response
 

Only genes that had a positive or negative change of 2.5-fold or greater and a false discovery rate of 5% or less were included. Autotaxin is represented by its gene symbol, ENPP2.

GPCR indicates G-protein-coupled receptor.

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