CB immature DCs expressed significantly higher level of some cytokines and chemokine genes than adult immature DCs
. | 3 h after infection . | . | 9 h after infection . | . | ||
|---|---|---|---|---|---|---|
. | MOCK . | SARS-CoV . | MOCK . | SARS-CoV . | ||
| IFN-α | – | – | – | – | ||
| IFN-β | – | – | – | – | ||
| IFN-γ | – | .03 | – | – | ||
| IL-12p40 | .02 | – | – | – | ||
| TNF-α | – | – | – | – | ||
| IL-6 | .04 | – | – | .006 | ||
| MIP-1α | .03 | .003 | .01 | .003 | ||
| RANTES | – | – | – | – | ||
| IP-10 | .03 | – | – | .03 | ||
| MCP-1 | .03 | .005 | .01 | .02 | ||
. | 3 h after infection . | . | 9 h after infection . | . | ||
|---|---|---|---|---|---|---|
. | MOCK . | SARS-CoV . | MOCK . | SARS-CoV . | ||
| IFN-α | – | – | – | – | ||
| IFN-β | – | – | – | – | ||
| IFN-γ | – | .03 | – | – | ||
| IL-12p40 | .02 | – | – | – | ||
| TNF-α | – | – | – | – | ||
| IL-6 | .04 | – | – | .006 | ||
| MIP-1α | .03 | .003 | .01 | .003 | ||
| RANTES | – | – | – | – | ||
| IP-10 | .03 | – | – | .03 | ||
| MCP-1 | .03 | .005 | .01 | .02 | ||
P values are given showing CB > adult DCs. Adult DCs (n = 7), CB DCs (n = 5).
– indicates no statistically significant difference detected.