Chemokines secreted by actived NK cells and DCs
. | CCL2 . | CCL3 . | CCL4 . | CCL5 . | CCL17 . | CCL22 . | XCL1 . | CXCL8 . | CXCL10 . | CX3CL1 . |
|---|---|---|---|---|---|---|---|---|---|---|
| Other name | MCP-1 | MIP1-α | MIP1-β | RANTES | Tarc | MDC | Lymphotactin | IL-8 | IP-10 | Fractalkine |
| Receptor | CCR2 | CCR1/5 | CCR5 | CCR1/3/5 | CCR4 | CCR4 | XCR1 | CXCR1/2 | CXCR3 | CX3CR1 |
| Human NK cells | ND | ++ | +++ | ++ | ND | ND | ND | +++ | ND | ND |
| Mouse NK cells | ND | +++ | +++ | ++ | ND | ND | +++ | NA | (+) | ND |
| Human/mouse DCs* | +++ | +++ | ND | +++ | +++ | +++ | ND | +++ | ND | +++ |
. | CCL2 . | CCL3 . | CCL4 . | CCL5 . | CCL17 . | CCL22 . | XCL1 . | CXCL8 . | CXCL10 . | CX3CL1 . |
|---|---|---|---|---|---|---|---|---|---|---|
| Other name | MCP-1 | MIP1-α | MIP1-β | RANTES | Tarc | MDC | Lymphotactin | IL-8 | IP-10 | Fractalkine |
| Receptor | CCR2 | CCR1/5 | CCR5 | CCR1/3/5 | CCR4 | CCR4 | XCR1 | CXCR1/2 | CXCR3 | CX3CR1 |
| Human NK cells | ND | ++ | +++ | ++ | ND | ND | ND | +++ | ND | ND |
| Mouse NK cells | ND | +++ | +++ | ++ | ND | ND | +++ | NA | (+) | ND |
| Human/mouse DCs* | +++ | +++ | ND | +++ | +++ | +++ | ND | +++ | ND | +++ |
NA indicates not applicable; ND, not determined. Symbols in parentheses indicate the presence of mRNA. Based on Sozzani et al,35 Saito et al,85 Bluman et al,86 Fehniger et al,87 Oliva et al,88 and Ortaldo et al.89
Various subsets