Comparison of ploidy status by trisomy index using different chromosome combinations and flow cytometry on ECOG validation group
. | DNA index, N . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|
| Chromosome combinations . | < 1.06 or > 1.74 . | 1.06 to 1.74 . | Sensitivity, % . | Specificity, % . | PPV, % . | NPV, % . | |
| 9, 11, 15 | - | - | 60 | 90 | 93 | 50 | |
| Nonhyperdiploid by TI | 27 | 27 | - | - | - | - | |
| Hyperdiploid by TI | 3 | 40 | - | - | - | - | |
| 3, 9, 15, 19 | 64 | 90 | 93 | 53 | |||
| Nonhyperdiploid by TI | 27 | 24 | - | - | - | - | |
| Hyperdiploid by TI | 3 | 43 | - | - | - | - | |
| 3, 9, 11, 15, 19 | - | - | 75 | 87 | 93 | 60 | |
| Nonhyperdiploid by TI | 26 | 17 | - | - | - | - | |
| Hyperdiploid by TI | 4 | 50 | - | - | - | - | |
. | DNA index, N . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|
| Chromosome combinations . | < 1.06 or > 1.74 . | 1.06 to 1.74 . | Sensitivity, % . | Specificity, % . | PPV, % . | NPV, % . | |
| 9, 11, 15 | - | - | 60 | 90 | 93 | 50 | |
| Nonhyperdiploid by TI | 27 | 27 | - | - | - | - | |
| Hyperdiploid by TI | 3 | 40 | - | - | - | - | |
| 3, 9, 15, 19 | 64 | 90 | 93 | 53 | |||
| Nonhyperdiploid by TI | 27 | 24 | - | - | - | - | |
| Hyperdiploid by TI | 3 | 43 | - | - | - | - | |
| 3, 9, 11, 15, 19 | - | - | 75 | 87 | 93 | 60 | |
| Nonhyperdiploid by TI | 26 | 17 | - | - | - | - | |
| Hyperdiploid by TI | 4 | 50 | - | - | - | - | |
- indicates not applicable.