Table 5.

Subsets of mast cells defined by morphological criteria.

Cell TypeMorphological Properties
Metachromatic blast Blast-like, few metachromatic
 granules 
Promastocyte =
 Atypical MC type II Mostly immature mast cells with
 bi- or multi-lobed nuclei, often
 hypogranulated 
Atypical mast cell type I Mast cells in which 2 of the 3
 following morphological aspects are
 found:
 a. cytoplasmic extensions
 (spindle shape)
 b. hypogranulated cytoplasm 
 c. oval decentralized nucleus 
Mature mast cell =
 typical tissue mast cell Round cell with round central
 nucleusand well-granulated
 cytoplasm 
Cell TypeMorphological Properties
Metachromatic blast Blast-like, few metachromatic
 granules 
Promastocyte =
 Atypical MC type II Mostly immature mast cells with
 bi- or multi-lobed nuclei, often
 hypogranulated 
Atypical mast cell type I Mast cells in which 2 of the 3
 following morphological aspects are
 found:
 a. cytoplasmic extensions
 (spindle shape)
 b. hypogranulated cytoplasm 
 c. oval decentralized nucleus 
Mature mast cell =
 typical tissue mast cell Round cell with round central
 nucleusand well-granulated
 cytoplasm 

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