Predictors of adverse outcomes Identified in the the Cooperative Study of Sickle Cell Disease (CSSCD).
| Predictors . | Outcomes . |
|---|---|
| Abbreviations: ACS, acute chest syndrome; AVN, avascular necrosis; Hgb, hemoglobin; WBC, white blood cells | |
| ↓ Hgb concentration | Death, stroke, leg ulcers |
| ↑ Hgb concentration | Pain, ACS, AVN |
| ↓ Hgb F concentration | Death, ACS, pain, leg ulcers |
| ↑ steady-state WBC | Death, ACS |
| α-thalassemia present | AVN |
| α-thalassemia absent | Stroke |
| ↑ Pain rate | Adult death, AVN |
| Acute anemia | Death, stroke |
| Predictors . | Outcomes . |
|---|---|
| Abbreviations: ACS, acute chest syndrome; AVN, avascular necrosis; Hgb, hemoglobin; WBC, white blood cells | |
| ↓ Hgb concentration | Death, stroke, leg ulcers |
| ↑ Hgb concentration | Pain, ACS, AVN |
| ↓ Hgb F concentration | Death, ACS, pain, leg ulcers |
| ↑ steady-state WBC | Death, ACS |
| α-thalassemia present | AVN |
| α-thalassemia absent | Stroke |
| ↑ Pain rate | Adult death, AVN |
| Acute anemia | Death, stroke |