Results of cytogenetics of patients with primary myelodysplastic syndrome (MDS) and those with MDS secondary to chemotherapy or radiation therapy in study EWOG-MDS 98.*
| . | Primary MDS (%) . | |||
|---|---|---|---|---|
| Karyotype . | All (n = 199) . | RC (n = 105) . | RAEB/RAEB-T (n = 94) . | MDS Secondary to Chemotherapy or Radiation Therapy (%) (n = 44) . |
| * MDS secondary to acquired or congenital bone marrow failure disorders and familial MDS were excluded from the analysis. EWOG-MDS unpublished data. | ||||
| Abbreviations: RC, refractory cytopenia; RAEB, refractory anemia with excess blasts; RAEB-T, RAEB in transformation; EWOG-MDS, European Working Group of Myelodysplasia in Childhood | ||||
| Complex (≥ 3 abnormalities) | 6 | 3 | 9 | 36 |
| Monosomy 7 | 24 | 17 | 32 | 23 |
| Trisomy 8 | 4 | 3 | 5 | 0 |
| Other abnormalities | 9 | 5 | 14 | 23 |
| Normal karyotype | 57 | 72 | 40 | 18 |
| . | Primary MDS (%) . | |||
|---|---|---|---|---|
| Karyotype . | All (n = 199) . | RC (n = 105) . | RAEB/RAEB-T (n = 94) . | MDS Secondary to Chemotherapy or Radiation Therapy (%) (n = 44) . |
| * MDS secondary to acquired or congenital bone marrow failure disorders and familial MDS were excluded from the analysis. EWOG-MDS unpublished data. | ||||
| Abbreviations: RC, refractory cytopenia; RAEB, refractory anemia with excess blasts; RAEB-T, RAEB in transformation; EWOG-MDS, European Working Group of Myelodysplasia in Childhood | ||||
| Complex (≥ 3 abnormalities) | 6 | 3 | 9 | 36 |
| Monosomy 7 | 24 | 17 | 32 | 23 |
| Trisomy 8 | 4 | 3 | 5 | 0 |
| Other abnormalities | 9 | 5 | 14 | 23 |
| Normal karyotype | 57 | 72 | 40 | 18 |