Table 1.

Value of fluorodeoxyglucose–positron emission tomography (FDG-PET) in the detection of residual disease after treatment in Hodgkin’s disease patients.

PFS@ 1 year
Author (ref)NumberNPVPPVMean FU (range, mo.)PETPET+
Abbreviations: NPV, negative predictive value; PPV, positive predictive value; FU, follow up; PFS, progression free survival; ns, not specified; PET+, residual disease on PET; PET, complete metabolic response 
Hueltenschmidt (9) 63 98% 86% 24 (3–41) ns ns 
Spaepen (10) 60 91% 100% 32 (13–50) 95% 40% 
Dittman (11) 24 94% 88% > 6 ns ns 
Naumann (12) 43 100% 25% 35 (15–58) 100% 75% 
Weihrauch (13) 29 84% 60% 28 (16–68) 95% 40% 
De Wit (14) 37 96% 46% 26 (2–34) 100% 75% 
Lavely (15) 20 81% ns 36 (9–75) ns ns 
Guay (16) 48 92% 92% ns 100% 45% 
Jerusalem (17) 36 94% 100% ns ns ns 
PFS@ 1 year
Author (ref)NumberNPVPPVMean FU (range, mo.)PETPET+
Abbreviations: NPV, negative predictive value; PPV, positive predictive value; FU, follow up; PFS, progression free survival; ns, not specified; PET+, residual disease on PET; PET, complete metabolic response 
Hueltenschmidt (9) 63 98% 86% 24 (3–41) ns ns 
Spaepen (10) 60 91% 100% 32 (13–50) 95% 40% 
Dittman (11) 24 94% 88% > 6 ns ns 
Naumann (12) 43 100% 25% 35 (15–58) 100% 75% 
Weihrauch (13) 29 84% 60% 28 (16–68) 95% 40% 
De Wit (14) 37 96% 46% 26 (2–34) 100% 75% 
Lavely (15) 20 81% ns 36 (9–75) ns ns 
Guay (16) 48 92% 92% ns 100% 45% 
Jerusalem (17) 36 94% 100% ns ns ns 
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