Table 1.

Important properties for an ideal iron chelator.

  • High and specific affinity for Fe3+

  • High chelating efficiency

  • Slow rate of metabolism

  • Tissue and cell penetration

  • No iron redistribution

  • Relatively non-toxic

  • Achievement of negative iron balance

  • Low cost

  • Oral availability

 

  • High and specific affinity for Fe3+

  • High chelating efficiency

  • Slow rate of metabolism

  • Tissue and cell penetration

  • No iron redistribution

  • Relatively non-toxic

  • Achievement of negative iron balance

  • Low cost

  • Oral availability

 
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