Currently available assays of hematopoietic progenitor and stem cells in umbilical cord blood.
Assay . | Ease and Rapidity for Clinical Application . | Correlation with Stable Engraftment . |
---|---|---|
Abbreviations: LTCIC, long-term culture-initiating cell; NOD/SRC, human to immundeficient NOD/SCID mouse repopulating cell assay | ||
Colony assays | +/− | Indirect, unmanipulated grafts only |
CD34+ | +++ | Indirect, unmanipulated grafts only |
LTCIC | – | Possibly direct |
NOD/SRC | – | Likely direct |
Assay . | Ease and Rapidity for Clinical Application . | Correlation with Stable Engraftment . |
---|---|---|
Abbreviations: LTCIC, long-term culture-initiating cell; NOD/SRC, human to immundeficient NOD/SCID mouse repopulating cell assay | ||
Colony assays | +/− | Indirect, unmanipulated grafts only |
CD34+ | +++ | Indirect, unmanipulated grafts only |
LTCIC | – | Possibly direct |
NOD/SRC | – | Likely direct |