Relation of VH mutation status and genomic aberrations in 300 chronic lymphocytic leukemia (CLL) cases.7
| Aberration . | VH Mutated . | VH Unmutated . | P-value# . |
|---|---|---|---|
| . | (homology < 98%) n = 132 (44%) . | (homology > 98%) n = 168 (56%) . | . |
| # Fisher’s exact test | |||
| Clonal aberrations | 80% | 84% | .37 |
| 13q deletion | 65% | 48% | .004 |
| 13q deletion single | 50% | 26% | <.001 |
| Trisomy 12 | 15% | 19% | .44 |
| 11q deletion | 4% | 27% | <.001 |
| 17p deletion | 3% | 10% | .03 |
| 17p or 11q deletion | 7% | 35% | <.001 |
| Aberration . | VH Mutated . | VH Unmutated . | P-value# . |
|---|---|---|---|
| . | (homology < 98%) n = 132 (44%) . | (homology > 98%) n = 168 (56%) . | . |
| # Fisher’s exact test | |||
| Clonal aberrations | 80% | 84% | .37 |
| 13q deletion | 65% | 48% | .004 |
| 13q deletion single | 50% | 26% | <.001 |
| Trisomy 12 | 15% | 19% | .44 |
| 11q deletion | 4% | 27% | <.001 |
| 17p deletion | 3% | 10% | .03 |
| 17p or 11q deletion | 7% | 35% | <.001 |