Five-year overall survival rates (OS) for patients treated with CHOP(3) plus radiotherapy in the Southwest Oncology Group (SWOG) or at the British Columbia Cancer Agency (BCCA), according to risk factors using a stage-modified International Prognostic Index (IPI) system.
| Risk Factor . | . | SWOG 5-Year OS . | BCCA 5-Year OS . |
|---|---|---|---|
| * Progression-free survival | |||
| Abbreviations: LDH, lactate dehydrogenase | |||
| Stage | I II | 82% 68% | – – |
| Age | ≤ 60 > 60 | 85% 70% | 90%* 75%* |
| LDH | Normal > Normal | 81% 65% | – – |
| Performance | 0–1 | 79% | – |
| Status | 2 | 50% | – |
| Risk Factors | 0 1 or 2 ≥ 1 3 3 or 4 | 94% – 70% 50% – | 97% 77% – – 58% |
| Risk Factor . | . | SWOG 5-Year OS . | BCCA 5-Year OS . |
|---|---|---|---|
| * Progression-free survival | |||
| Abbreviations: LDH, lactate dehydrogenase | |||
| Stage | I II | 82% 68% | – – |
| Age | ≤ 60 > 60 | 85% 70% | 90%* 75%* |
| LDH | Normal > Normal | 81% 65% | – – |
| Performance | 0–1 | 79% | – |
| Status | 2 | 50% | – |
| Risk Factors | 0 1 or 2 ≥ 1 3 3 or 4 | 94% – 70% 50% – | 97% 77% – – 58% |