Table 1.

SINE compounds and venetoclax display differential growth inhibition of malignant myeloid cell lines

Cell lineAverage GI50 at 72 h, nM
SelinexorEltanexorVenetoclax
MOLM-13 52 32 25 
MV-4-11 57 22 52 
K-562 241 104 >5000 
MOLM-16 165 59 >5000 
U-937 444 131 >5000 
NB4 571 264 >1000 
Cell lineAverage GI50 at 72 h, nM
SelinexorEltanexorVenetoclax
MOLM-13 52 32 25 
MV-4-11 57 22 52 
K-562 241 104 >5000 
MOLM-16 165 59 >5000 
U-937 444 131 >5000 
NB4 571 264 >1000 

Values are averaged from 3 independent experiments.

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