Characteristics of included studies comparing home vs hospital treatment of patients with uncomplicated DVT
| Author, y . | Country . | No. of patients . | Intervention: home treatment . | Control: hospital treatment . | Mean hospital length of stay ± SD, d . | Mean age ± SD, y . | Known cancer, % . | Female, % . | Follow-up . |
|---|---|---|---|---|---|---|---|---|---|
| Koopman et al,4 1996 | Netherlands, France, Italy, New Zealand, Australia | Home: 198 | LMWH at home when appropriate, oral anticoagulant treatment was initiated on the first day and continued for a total of 3 mo | UFH in hospital, oral anticoagulant treatment was initiated on the first day and continued for a total of 3 mo | Home: 2.7 | Hospital: 59 ± 17 | Hospital: 18 | 49.3 | 6 mo |
| Hospital: 202 | Hospital: 8.1 | Home: 62 ± 16 | Home: 17 | ||||||
| Levine et al,5 1996 | Canada | Home: 253 | LMWH primarily at home, warfarin started on end of day 2 and continued for minimum 3 mo | UFH in hospital, warfarin started on end of day 2 and continued for minimum 3 mo | Home: 1.1 ± 2.9 | Hospital: 57 ± 17 | Hospital: 19 | 39.8 | 3 mo |
| Hospital: 247 | Hospital: 6.5 ± 3.4 | Home: 59 ± 15 | Home: 23 | ||||||
| Boccalon et al,17 2000 | France | Home: 99 | Injection of LMWH followed by OA for 6 mo at home; compression stockings | Injection of LMWH followed by OA for 6 mo initial in hospital for 10+2 d, then at home; compression stockings | Home: 1.0 ± 1.6 | 63.8 ± 14.1 | Not reported | 43.8 | 6 mo |
| Hospital: 102 | Hospital: 9.6 ± 3.6 | ||||||||
| Ramacciotti et al,18 2004 | Brazil | Home: 97 | LMWH injection for 5-10 d, given at home or in hospital; warfarin for at least 3 mo starting at day 1 or 2 of treatment | UFH for 5-10 d in hospital; warfarin for at least 3 mo starting at day 1 or 2 of treatment | Home: 3.0 ± 3.0 | Hospital: 44 ± 18 | Not reported | 65.7 | 6 mo |
| Hospital: 104 | Hospital: 7 ± 3 | Home: 46 ± 19 | |||||||
| Chong et al,19 2005 | Australia, New Zealand, Poland, South Africa | Home: 150 | Injection of LMWH for a minimum of 5 d plus warfarin for 3 mo | UFH for a minimum of 5 d, plus warfarin started on day 1 of treatment, for 3 mo | Not reported | Hospital: 54.9 ± 17.7 | Not reported | 47.7 | 24 wk |
| Hospital: 148 | Home: 55.8 ± 16.8 | ||||||||
| Daskalopoulos et al,20 2005 | Greece | Home: 53 | Injection of LMWH for 6 mo | UFH 5 to 7 d; oral anticoagulant was commenced on the third day following UFH therapy for 6 mo | Not reported; patients allocated to home underwent no hospitalization | Median (range): Hospital: 58.5 (25-91) | Hospital: 6 | 59.8 | 12 mo |
| Hospital: 55 | Home: 60.5 (23-95) | Home: 8 | |||||||
| Romera-Villegas et al,21 2008 | Spain | Home: 111 | Received care at home with early walking and compression stockings | Hospitalized and received 5 d of bed rest | Not reported | 64.2 | Not reported | 46.1 | 10 d |
| Hospital: 103 |
| Author, y . | Country . | No. of patients . | Intervention: home treatment . | Control: hospital treatment . | Mean hospital length of stay ± SD, d . | Mean age ± SD, y . | Known cancer, % . | Female, % . | Follow-up . |
|---|---|---|---|---|---|---|---|---|---|
| Koopman et al,4 1996 | Netherlands, France, Italy, New Zealand, Australia | Home: 198 | LMWH at home when appropriate, oral anticoagulant treatment was initiated on the first day and continued for a total of 3 mo | UFH in hospital, oral anticoagulant treatment was initiated on the first day and continued for a total of 3 mo | Home: 2.7 | Hospital: 59 ± 17 | Hospital: 18 | 49.3 | 6 mo |
| Hospital: 202 | Hospital: 8.1 | Home: 62 ± 16 | Home: 17 | ||||||
| Levine et al,5 1996 | Canada | Home: 253 | LMWH primarily at home, warfarin started on end of day 2 and continued for minimum 3 mo | UFH in hospital, warfarin started on end of day 2 and continued for minimum 3 mo | Home: 1.1 ± 2.9 | Hospital: 57 ± 17 | Hospital: 19 | 39.8 | 3 mo |
| Hospital: 247 | Hospital: 6.5 ± 3.4 | Home: 59 ± 15 | Home: 23 | ||||||
| Boccalon et al,17 2000 | France | Home: 99 | Injection of LMWH followed by OA for 6 mo at home; compression stockings | Injection of LMWH followed by OA for 6 mo initial in hospital for 10+2 d, then at home; compression stockings | Home: 1.0 ± 1.6 | 63.8 ± 14.1 | Not reported | 43.8 | 6 mo |
| Hospital: 102 | Hospital: 9.6 ± 3.6 | ||||||||
| Ramacciotti et al,18 2004 | Brazil | Home: 97 | LMWH injection for 5-10 d, given at home or in hospital; warfarin for at least 3 mo starting at day 1 or 2 of treatment | UFH for 5-10 d in hospital; warfarin for at least 3 mo starting at day 1 or 2 of treatment | Home: 3.0 ± 3.0 | Hospital: 44 ± 18 | Not reported | 65.7 | 6 mo |
| Hospital: 104 | Hospital: 7 ± 3 | Home: 46 ± 19 | |||||||
| Chong et al,19 2005 | Australia, New Zealand, Poland, South Africa | Home: 150 | Injection of LMWH for a minimum of 5 d plus warfarin for 3 mo | UFH for a minimum of 5 d, plus warfarin started on day 1 of treatment, for 3 mo | Not reported | Hospital: 54.9 ± 17.7 | Not reported | 47.7 | 24 wk |
| Hospital: 148 | Home: 55.8 ± 16.8 | ||||||||
| Daskalopoulos et al,20 2005 | Greece | Home: 53 | Injection of LMWH for 6 mo | UFH 5 to 7 d; oral anticoagulant was commenced on the third day following UFH therapy for 6 mo | Not reported; patients allocated to home underwent no hospitalization | Median (range): Hospital: 58.5 (25-91) | Hospital: 6 | 59.8 | 12 mo |
| Hospital: 55 | Home: 60.5 (23-95) | Home: 8 | |||||||
| Romera-Villegas et al,21 2008 | Spain | Home: 111 | Received care at home with early walking and compression stockings | Hospitalized and received 5 d of bed rest | Not reported | 64.2 | Not reported | 46.1 | 10 d |
| Hospital: 103 |
OA, oral anticoagulation; SD, standard deviation; UFH, unfractionated heparin.