Estimated pairwise treatment effects on PFS between the 4 conditioning regimen groups after correction of the multiple PSs and other baseline and transplant characteristics
| Conditioning type . | Reference: Bu16000 . | Reference: Bu≥20000 . | Reference: FM100 . | |||
|---|---|---|---|---|---|---|
| Adjusted HR (95% CI)* . | P* . | Adjusted HR (95% CI)* . | P* . | Adjusted HR (95% CI)* . | P* . | |
| Bu≥20000 | 0.77 (0.55-1.09) | .137 | Reference | — | — | — |
| FM100 | 0.57 (0.36-0.89) | .013 | 0.73 (0.46-0.98) | .044 | Reference | — |
| FM140 | 0.68 (0.45-1.01) | .056 | 0.87 (0.57-1.34) | .554 | 1.20 (1.03-1.42) | .038 |
| Conditioning type . | Reference: Bu16000 . | Reference: Bu≥20000 . | Reference: FM100 . | |||
|---|---|---|---|---|---|---|
| Adjusted HR (95% CI)* . | P* . | Adjusted HR (95% CI)* . | P* . | Adjusted HR (95% CI)* . | P* . | |
| Bu≥20000 | 0.77 (0.55-1.09) | .137 | Reference | — | — | — |
| FM100 | 0.57 (0.36-0.89) | .013 | 0.73 (0.46-0.98) | .044 | Reference | — |
| FM140 | 0.68 (0.45-1.01) | .056 | 0.87 (0.57-1.34) | .554 | 1.20 (1.03-1.42) | .038 |
CI, confidence interval.
Variables included in the multivariable Cox regression model were propensity score, age (>65 vs ≤65 y), KPS >90 vs ≤90), secondary AML, ELN2017 genetic risk, remission status before transplant, induction failure, donor type, stem cell source, patient and donor cytomegalovirus serostatus, and transplant protocol (on protocol vs standard of care).