Comparison of longitudinal changes in IS
| Median, IU/dL . | Baseline (t0) . | Final follow-up (t4)* . | Difference in medians (matched pairs, n = 34)† . | Difference in medians (all data)‡ . | KW testing§ . |
|---|---|---|---|---|---|
| FVIII | 178.6 | 137.7 | −21.2 (P = .0149) | −40.9 (P = .0038) | 12.58 (P = .0135) |
| VWF:Ag | 196.9 | 157.7 | −18.24 (P = .0093) | −47.5 (P = .0046) | 9.568 (P = .0484) |
| VWF:Act | 188.7 | 143.7 | −11.6 (P = .0289) | −45.05 (P = .0783) | 5.21 (P = .2665) |
| ADAMTS13Ac | 85.9 | 96.8 | 4.9 (P = .0092) | 10.85 (P = .0043) | 11.87 (P = .0184) |
| VWF:Ag/ADAMTS13Ac ratio | 2.42 | 1.66 | −0.2775 (P = .0007) | −0.869 (P = .0008) | 12.42 (P = .0145) |
| Median, IU/dL . | Baseline (t0) . | Final follow-up (t4)* . | Difference in medians (matched pairs, n = 34)† . | Difference in medians (all data)‡ . | KW testing§ . |
|---|---|---|---|---|---|
| FVIII | 178.6 | 137.7 | −21.2 (P = .0149) | −40.9 (P = .0038) | 12.58 (P = .0135) |
| VWF:Ag | 196.9 | 157.7 | −18.24 (P = .0093) | −47.5 (P = .0046) | 9.568 (P = .0484) |
| VWF:Act | 188.7 | 143.7 | −11.6 (P = .0289) | −45.05 (P = .0783) | 5.21 (P = .2665) |
| ADAMTS13Ac | 85.9 | 96.8 | 4.9 (P = .0092) | 10.85 (P = .0043) | 11.87 (P = .0184) |
| VWF:Ag/ADAMTS13Ac ratio | 2.42 | 1.66 | −0.2775 (P = .0007) | −0.869 (P = .0008) | 12.42 (P = .0145) |