Summary of the reported end-organ manifestations in MGRS entities
| MGRS subtype . | Organs affected/manifestations . | References . |
|---|---|---|
| Amyloidosis | Heart, liver, autonomic nerves, skin, gastrointestinal tract, pulmonary | 62 |
| MIDD | Liver, heart, peripheral nerves, lung, skin (seen in 35% of cases) | 28,63,-65 |
| Cryoglobulinemic GN | Vasculitis, Raynaud’s phenomenon, purpura, livedo reticularis, arthralgia, peripheral neuropathy | 29,48,49 |
| C3G | Skin necrosis | 11 |
| LCPT with FS | Osteomalacia | 28 |
| Crystalglobulinemia | Skin rash, polyarthralgia, neuropathy | 29,66 |
| CSH | FS, spleen, lymph nodes, macrophage activation, cornea, lungs, thyroid, parotid gland, synovium, liver, brain, skin, subcutaneous fat | 9,55 |
| POEMS syndrome | Sensory motor polyneuropathy, organomegaly, endocrinopathy, skin | 61 |
| MGRS subtype . | Organs affected/manifestations . | References . |
|---|---|---|
| Amyloidosis | Heart, liver, autonomic nerves, skin, gastrointestinal tract, pulmonary | 62 |
| MIDD | Liver, heart, peripheral nerves, lung, skin (seen in 35% of cases) | 28,63,-65 |
| Cryoglobulinemic GN | Vasculitis, Raynaud’s phenomenon, purpura, livedo reticularis, arthralgia, peripheral neuropathy | 29,48,49 |
| C3G | Skin necrosis | 11 |
| LCPT with FS | Osteomalacia | 28 |
| Crystalglobulinemia | Skin rash, polyarthralgia, neuropathy | 29,66 |
| CSH | FS, spleen, lymph nodes, macrophage activation, cornea, lungs, thyroid, parotid gland, synovium, liver, brain, skin, subcutaneous fat | 9,55 |
| POEMS syndrome | Sensory motor polyneuropathy, organomegaly, endocrinopathy, skin | 61 |