Table 2.

Health care–associated infections in patients without diabetes

Outcome measuresTXA (n = 204)Placebo (n = 200)RR (95% CI)P
Primary end point     
 Health care–associated infection 43 (21.1) 63 (31.5) 0.67 (0.48-0.94) .017 
Secondary end points* 23 (11.3) 22 (11.0) 1.03 (0.59-1.78) .93 
 Pneumonia     
 SSI 22 (10.8) 36 (18.0) 0.60 (0.37-0.98) .039 
  Superficial 17 (8.3) 32 (16.0) 0.52 (0.30-0.91) .018 
  Deep 4 (2.0) 4 (2.0) 0.98 (0.25-3.87) .98 
  Organ space 1 (0.5) 2 (1.0) 0.49 (0.05-5.36) .62 
 Sepsis 21 (10.3) 31 (15.5) 0.66 (0.40-1.12) .12 
 Bacteremia 2 (1.0) 1 (0.5) 1.96 (0.18-21.5) .57 
 Catheter line infection 2 (1.0) 0 (0.0) — .50 
Outcome measuresTXA (n = 204)Placebo (n = 200)RR (95% CI)P
Primary end point     
 Health care–associated infection 43 (21.1) 63 (31.5) 0.67 (0.48-0.94) .017 
Secondary end points* 23 (11.3) 22 (11.0) 1.03 (0.59-1.78) .93 
 Pneumonia     
 SSI 22 (10.8) 36 (18.0) 0.60 (0.37-0.98) .039 
  Superficial 17 (8.3) 32 (16.0) 0.52 (0.30-0.91) .018 
  Deep 4 (2.0) 4 (2.0) 0.98 (0.25-3.87) .98 
  Organ space 1 (0.5) 2 (1.0) 0.49 (0.05-5.36) .62 
 Sepsis 21 (10.3) 31 (15.5) 0.66 (0.40-1.12) .12 
 Bacteremia 2 (1.0) 1 (0.5) 1.96 (0.18-21.5) .57 
 Catheter line infection 2 (1.0) 0 (0.0) — .50 

All data are n (%). The dash indicates that the RR cannot be determined. Bold indicates significant results.

*

Patients could have >1 site of infection.

Fisher’s exact test.

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