Maternal and pregnancy characteristics associated with a TR
| Risk factor . | Total deliveries (n = 517 874) . | Women transfused (n = 12 183) . | TR cases (n = 96) . | TR* crude OR . | 95% CI . | TR† adjusted‡ OR . | 95% CI . |
|---|---|---|---|---|---|---|---|
| Maternal characteristics | |||||||
| Age, y | |||||||
| ≤34 | 403 396 | 9 253 | 67 | 1.0 (ref) | |||
| 35-39 | 94 875 | 2 351 | 24 | 1.5 | 1.0-2.4 | 1.4 | 0.9-2.8 |
| ≥40 | 19 603 | 579 | 5 | 1.5 | 0.6-3.8 | 1.2 | 0.5-3.0 |
| Ethnicity | |||||||
| European | 433 170 | 9 637 | 72 | 1.0 (ref) | |||
| Non-European | 84 704 | 2 546 | 24 | 1.6 | 1.0-2.6 | 1.3 | 0.8-2.1 |
| Previous deliveries | |||||||
| 0 | 237 778 | 7 420 | 56 | 1.5 | 1.0-2.3 | 0.8 | 0.5-1.3 |
| 1 | 188 435 | 3 196 | 30 | 1.0 (ref) | ref | ||
| ≥2 | 91 661 | 1 567 | 10 | 0.7 | 0.3-1.4 | 0.6 | 0.3-1.2 |
| Previous CS | |||||||
| No | 474 886 | 10 735 | 84 | 1.0 (ref) | |||
| Yes | 42 988 | 1 448 | 12 | 1.6 | 0.9-2.9 | 1.1 | 0.5-2.1 |
| Pregnancy complications | |||||||
| Multiple pregnancy | |||||||
| No | 510 268 | 11 479 | 87 | ||||
| Yes | 7 606 | 704 | 9 | 6.9 | 3.5-13.8 | 1.4 | 0.7-2.8 |
| Placenta previa/accreta | |||||||
| No | 516 675 | 11 911 | 92 | 1.0 (ref) | |||
| Yes | 1 199 | 272 | 4 | 18.5 | 6.8-50.3 | 2.2 | 0.8-6.4 |
| Preeclampsia | |||||||
| No | 505 567 | 11 116 | 78 | 1.0 (ref) | |||
| Yes | 12 307 | 1 067 | 18 | 9.3 | 5.6-15.6 | 2.0 | 1.2-3.5 |
| Variables at delivery | |||||||
| Induction of labor | 53 936 | 2 284 | 29 | 3.7 | 2.4-5.8 | 1.7 | 1.1-2.9 |
| Mode of delivery | |||||||
| Spontaneous vaginal | 395 169 | 6 456 | 14 | 1.0 (ref) | |||
| Instrumental vaginal | 40 819 | 2 082 | 52 | 2.6 | 1.5-4.7 | 0.8 | 0.4-1.5 |
| CS | 81 886 | 3 645 | 30 | 2.9 | 1.8-4.7 | 0.8 | 0.5-1.3 |
| Placental disorders | |||||||
| Placental abruption | 1 328 | 229 | 4 | 17.0 | 6.2-46.2 | 2.6 | 0.9-7.3 |
| PPH and uterine atony | 12 080 | 1 730 | 14 | 8.4 | 4.7-14.8 | 1.1 | 0.6-1.9 |
| Newborn characteristics | |||||||
| Premature (≤34 + 0 gw) | 11 075 | 797 | 12 | 6.5 | 3.6-12.0 | 1.7 | 1.0-3.7 |
| Risk factor . | Total deliveries (n = 517 874) . | Women transfused (n = 12 183) . | TR cases (n = 96) . | TR* crude OR . | 95% CI . | TR† adjusted‡ OR . | 95% CI . |
|---|---|---|---|---|---|---|---|
| Maternal characteristics | |||||||
| Age, y | |||||||
| ≤34 | 403 396 | 9 253 | 67 | 1.0 (ref) | |||
| 35-39 | 94 875 | 2 351 | 24 | 1.5 | 1.0-2.4 | 1.4 | 0.9-2.8 |
| ≥40 | 19 603 | 579 | 5 | 1.5 | 0.6-3.8 | 1.2 | 0.5-3.0 |
| Ethnicity | |||||||
| European | 433 170 | 9 637 | 72 | 1.0 (ref) | |||
| Non-European | 84 704 | 2 546 | 24 | 1.6 | 1.0-2.6 | 1.3 | 0.8-2.1 |
| Previous deliveries | |||||||
| 0 | 237 778 | 7 420 | 56 | 1.5 | 1.0-2.3 | 0.8 | 0.5-1.3 |
| 1 | 188 435 | 3 196 | 30 | 1.0 (ref) | ref | ||
| ≥2 | 91 661 | 1 567 | 10 | 0.7 | 0.3-1.4 | 0.6 | 0.3-1.2 |
| Previous CS | |||||||
| No | 474 886 | 10 735 | 84 | 1.0 (ref) | |||
| Yes | 42 988 | 1 448 | 12 | 1.6 | 0.9-2.9 | 1.1 | 0.5-2.1 |
| Pregnancy complications | |||||||
| Multiple pregnancy | |||||||
| No | 510 268 | 11 479 | 87 | ||||
| Yes | 7 606 | 704 | 9 | 6.9 | 3.5-13.8 | 1.4 | 0.7-2.8 |
| Placenta previa/accreta | |||||||
| No | 516 675 | 11 911 | 92 | 1.0 (ref) | |||
| Yes | 1 199 | 272 | 4 | 18.5 | 6.8-50.3 | 2.2 | 0.8-6.4 |
| Preeclampsia | |||||||
| No | 505 567 | 11 116 | 78 | 1.0 (ref) | |||
| Yes | 12 307 | 1 067 | 18 | 9.3 | 5.6-15.6 | 2.0 | 1.2-3.5 |
| Variables at delivery | |||||||
| Induction of labor | 53 936 | 2 284 | 29 | 3.7 | 2.4-5.8 | 1.7 | 1.1-2.9 |
| Mode of delivery | |||||||
| Spontaneous vaginal | 395 169 | 6 456 | 14 | 1.0 (ref) | |||
| Instrumental vaginal | 40 819 | 2 082 | 52 | 2.6 | 1.5-4.7 | 0.8 | 0.4-1.5 |
| CS | 81 886 | 3 645 | 30 | 2.9 | 1.8-4.7 | 0.8 | 0.5-1.3 |
| Placental disorders | |||||||
| Placental abruption | 1 328 | 229 | 4 | 17.0 | 6.2-46.2 | 2.6 | 0.9-7.3 |
| PPH and uterine atony | 12 080 | 1 730 | 14 | 8.4 | 4.7-14.8 | 1.1 | 0.6-1.9 |
| Newborn characteristics | |||||||
| Premature (≤34 + 0 gw) | 11 075 | 797 | 12 | 6.5 | 3.6-12.0 | 1.7 | 1.0-3.7 |
gw, gestational weeks; ref, reference.
Background = total deliveries.
Background = all women who received a blood transfusion postpartum (n = 12 183).
Adjusted for age, ethnicity, previous deliveries, previous CS, multiple pregnancy, placenta previa/accreta, preeclampsia, induction of labor, placental disorders, and premature birth ≤34 gw.