Number of women analyzed by each of the 7 different typing strategies (rows) and final conclusion regarding their dose of HLA-DRB3*01:01
| Sequencing exon 2 of the HLA-DRB3 gene . | HLA-DRB3 typing* . | First-field resolution HLA-DRB1 typing* . | Second-field resolution HLA-DRB1 typing* . | Conclusion . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DRB3*01:01 negative . | One DRB3 allele . | DRB3*01:01 in combination with another DRB3 allele . | DRB3 negative . | DRB3 allele other than *01:01 . | No alleles associated with DRB3 . | Only 1 allele associated with DRB3 . | Two alleles associated with DRB3 . | Two alleles associated with DRB3*01:01 . | DRB3*01:01 negative . | One dose of DRB3*01:01 . | Two doses of DRB3*01:01 . | |
| Only DRB3*01:01 . | DRB3 allele other than *01:01 . | |||||||||||
| 7 | — | — | — | 7 | — | — | — | — | — | 7 | — | — |
| — | — | 2 | — | — | — | — | — | — | — | 2 | — | — |
| — | — | — | 19 | — | — | — | — | — | — | — | 19 | — |
| — | 87 | — | — | — | — | — | 87 | — | — | — | 87 | — |
| — | 13 | — | — | — | — | — | — | 13 | 13 | — | — | 13 |
| — | — | — | — | — | — | 1 | — | — | — | 1 | — | — |
| — | — | — | — | — | 1 | — | — | — | — | 1 | — | — |
| Sequencing exon 2 of the HLA-DRB3 gene . | HLA-DRB3 typing* . | First-field resolution HLA-DRB1 typing* . | Second-field resolution HLA-DRB1 typing* . | Conclusion . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DRB3*01:01 negative . | One DRB3 allele . | DRB3*01:01 in combination with another DRB3 allele . | DRB3 negative . | DRB3 allele other than *01:01 . | No alleles associated with DRB3 . | Only 1 allele associated with DRB3 . | Two alleles associated with DRB3 . | Two alleles associated with DRB3*01:01 . | DRB3*01:01 negative . | One dose of DRB3*01:01 . | Two doses of DRB3*01:01 . | |
| Only DRB3*01:01 . | DRB3 allele other than *01:01 . | |||||||||||
| 7 | — | — | — | 7 | — | — | — | — | — | 7 | — | — |
| — | — | 2 | — | — | — | — | — | — | — | 2 | — | — |
| — | — | — | 19 | — | — | — | — | — | — | — | 19 | — |
| — | 87 | — | — | — | — | — | 87 | — | — | — | 87 | — |
| — | 13 | — | — | — | — | — | — | 13 | 13 | — | — | 13 |
| — | — | — | — | — | — | 1 | — | — | — | 1 | — | — |
| — | — | — | — | — | 1 | — | — | — | — | 1 | — | — |
Typing was performed at the Tissue Typing Laboratory, Department of Immunology, Rikshospitalet, Oslo University Hospital, Oslo, Norway, a laboratory that is accredited by the European Federation for Immunogenetics.